Machine-Learning based model order reduction of a biomechanical model of the human tongue.


Journal

Computer methods and programs in biomedicine
ISSN: 1872-7565
Titre abrégé: Comput Methods Programs Biomed
Pays: Ireland
ID NLM: 8506513

Informations de publication

Date de publication:
Jan 2021
Historique:
received: 09 04 2020
accepted: 30 09 2020
pubmed: 16 10 2020
medline: 15 5 2021
entrez: 15 10 2020
Statut: ppublish

Résumé

This paper presents the results of a Machine-Learning based Model Order Reduction (MOR) method applied to a complex 3D Finite Element (FE) biomechanical model of the human tongue, in order to create a Digital Twin Model (DTM) that enables real-time simulations. The DTM is designed for future inclusion in a computer assisted protocol for tongue surgery planning. The proposed method uses an "a posteriori" MOR that allows, from a limited number of simulations with the FE model, to predict in real time mechanical responses of the human tongue to muscle activations. The MOR method is evaluated for simulations associated with separate single tongue muscle activations. It is shown to be able to account with a sub-millimetric spatial accuracy for the non-linear dynamical behavior of the tongue model observed in these simulations. Further evaluations of the MOR method will include tongue movements induced by multiple muscle activations. At this stage our MOR method offers promising perspectives for the use of the tongue model in a clinical context to predict the impact of tongue surgery on tongue mobility. As a long term application, this DTM of the tongue could be used to predict the functional consequences of the surgery in terms of speech production and swallowing.

Sections du résumé

BACKGROUND AND OBJECTIVES OBJECTIVE
This paper presents the results of a Machine-Learning based Model Order Reduction (MOR) method applied to a complex 3D Finite Element (FE) biomechanical model of the human tongue, in order to create a Digital Twin Model (DTM) that enables real-time simulations. The DTM is designed for future inclusion in a computer assisted protocol for tongue surgery planning.
METHODS METHODS
The proposed method uses an "a posteriori" MOR that allows, from a limited number of simulations with the FE model, to predict in real time mechanical responses of the human tongue to muscle activations.
RESULTS RESULTS
The MOR method is evaluated for simulations associated with separate single tongue muscle activations. It is shown to be able to account with a sub-millimetric spatial accuracy for the non-linear dynamical behavior of the tongue model observed in these simulations.
CONCLUSION CONCLUSIONS
Further evaluations of the MOR method will include tongue movements induced by multiple muscle activations. At this stage our MOR method offers promising perspectives for the use of the tongue model in a clinical context to predict the impact of tongue surgery on tongue mobility. As a long term application, this DTM of the tongue could be used to predict the functional consequences of the surgery in terms of speech production and swallowing.

Identifiants

pubmed: 33059060
pii: S0169-2607(20)31619-9
doi: 10.1016/j.cmpb.2020.105786
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

105786

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

Auteurs

Maxime Calka (M)

Univ. Grenoble Alpes, CNRS, Grenoble INP, TIMC-IMAG, Grenoble F-38000, France; Univ. Grenoble Alpes, CNRS, Grenoble INP, GIPSA-lab, Grenoble F-38000, France; ANSYS, Villeurbanne F-69100, France. Electronic address: maxime.calka@univ-grenoble-alpes.fr.

Pascal Perrier (P)

Univ. Grenoble Alpes, CNRS, Grenoble INP, GIPSA-lab, Grenoble F-38000, France.

Jacques Ohayon (J)

Univ. Grenoble Alpes, CNRS, Grenoble INP, TIMC-IMAG, Grenoble F-38000, France; Savoie Mont-Blanc University, Polytech Annecy-Chambéry, Le Bourget du Lac 73376, France.

Christelle Grivot-Boichon (C)

ANSYS, Villeurbanne F-69100, France.

Michel Rochette (M)

ANSYS, Villeurbanne F-69100, France.

Yohan Payan (Y)

Univ. Grenoble Alpes, CNRS, Grenoble INP, TIMC-IMAG, Grenoble F-38000, France.

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Classifications MeSH