New insights into Hexakis macrocycles as a novel nano-carrier for highly potent anti-cancer treatment: A new challenge in drug delivery.
Drug delivery
Dual delivery
Free energy calculation
Hexakis (m-PE) macrocycles
Molecular dynamics (MD) simulations
Self-assembly system
Journal
Colloids and surfaces. B, Biointerfaces
ISSN: 1873-4367
Titre abrégé: Colloids Surf B Biointerfaces
Pays: Netherlands
ID NLM: 9315133
Informations de publication
Date de publication:
Jan 2021
Jan 2021
Historique:
received:
30
03
2020
revised:
30
09
2020
accepted:
04
10
2020
pubmed:
16
10
2020
medline:
22
6
2021
entrez:
15
10
2020
Statut:
ppublish
Résumé
The purpose of this study is to design and evaluate a new tubular assembly structure of Hexakis (m-phenylene ethynylene) (m-PE) macrocycles and to explore its potential application as an innovative drug delivery system. First, we focused on how (m-PE) macrocycles can be self-assembled in both chloroform (CHCl
Identifiants
pubmed: 33059208
pii: S0927-7765(20)30758-X
doi: 10.1016/j.colsurfb.2020.111402
pii:
doi:
Substances chimiques
Drug Carriers
0
Pharmaceutical Preparations
0
Doxorubicin
80168379AG
Curcumin
IT942ZTH98
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
111402Informations de copyright
Copyright © 2020. Published by Elsevier B.V.