Comprehensive Pulmonary Rehabilitation is an Effective Way for Better Postoperative Outcomes in Surgical Lung Cancer Patients with Risk Factors: A Propensity Score-Matched Retrospective Cohort Study.
lobectomy
lung cancer
pulmonary rehabilitation
thoracic surgery
Journal
Cancer management and research
ISSN: 1179-1322
Titre abrégé: Cancer Manag Res
Pays: New Zealand
ID NLM: 101512700
Informations de publication
Date de publication:
2020
2020
Historique:
received:
12
06
2020
accepted:
19
08
2020
entrez:
16
10
2020
pubmed:
17
10
2020
medline:
17
10
2020
Statut:
epublish
Résumé
To investigate the effectiveness and cost minimization of comprehensive pulmonary rehabilitation (CPR) in lung cancer patients who underwent surgery. A retrospective observational study based on medical records was conducted, with 2410 lung cancer patients who underwent an operation with/without CPR during the peri-operative period. Variables including clinical characteristics, length of stay (LOS), postoperative pulmonary complications (PPCs), and hospitalization expenses were compared between the intervention group (IG) and control group (CG). The CPR regimen consists of inspiratory muscle training (IMT), aerobic endurance training, and pharmacotherapy. Propensity score matching analysis was performed between two groups, and the ratio of matched patients was 1:4. Finally, 205 cases of IG and 820 cases of CG in the matched cohort of our study were identified. The length of postoperative hospital stay [median: 5 interquartile (4-7) vs 7 (4-8) days, The retrospective cohort study revealed a lower PPC rate and the shorter postoperative length of stay in the patients receiving CPR, demonstrating the clinical value of CRP as an effective strategy for surgical lung cancer patients with risk factors.
Sections du résumé
BACKGROUND
BACKGROUND
To investigate the effectiveness and cost minimization of comprehensive pulmonary rehabilitation (CPR) in lung cancer patients who underwent surgery.
PATIENTS AND METHODS
METHODS
A retrospective observational study based on medical records was conducted, with 2410 lung cancer patients who underwent an operation with/without CPR during the peri-operative period. Variables including clinical characteristics, length of stay (LOS), postoperative pulmonary complications (PPCs), and hospitalization expenses were compared between the intervention group (IG) and control group (CG). The CPR regimen consists of inspiratory muscle training (IMT), aerobic endurance training, and pharmacotherapy.
RESULTS
RESULTS
Propensity score matching analysis was performed between two groups, and the ratio of matched patients was 1:4. Finally, 205 cases of IG and 820 cases of CG in the matched cohort of our study were identified. The length of postoperative hospital stay [median: 5 interquartile (4-7) vs 7 (4-8) days,
CONCLUSION
CONCLUSIONS
The retrospective cohort study revealed a lower PPC rate and the shorter postoperative length of stay in the patients receiving CPR, demonstrating the clinical value of CRP as an effective strategy for surgical lung cancer patients with risk factors.
Identifiants
pubmed: 33061586
doi: 10.2147/CMAR.S267322
pii: 267322
pmc: PMC7520117
doi:
Types de publication
Journal Article
Langues
eng
Pagination
8903-8912Informations de copyright
© 2020 Zhou et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in this work.
Références
J Thorac Dis. 2017 Nov;9(11):4486-4493
pubmed: 29268518
Clin Chest Med. 2019 Mar;40(1):163-177
pubmed: 30691710
J Thorac Cardiovasc Surg. 2015 Apr;149(4):1168-73.e3
pubmed: 25583106
Eur J Cardiothorac Surg. 2013 Feb;43(2):293-6
pubmed: 22588033
J Thorac Cardiovasc Surg. 2008 Feb;135(2):247-54
pubmed: 18242243
J Thorac Cardiovasc Surg. 2019 Jan;157(1):272-284
pubmed: 30396739
Lung Cancer. 2011 Dec;74(3):441-5
pubmed: 21663994
Chest. 2006 May;129(5):1305-12
pubmed: 16685023
J Thorac Cardiovasc Surg. 2016 Mar;151(3):708-715.e6
pubmed: 26553460
Thorax. 2019 Oct;74(10):996-998
pubmed: 31278173
Eur J Cardiothorac Surg. 2011 Jun;39(6):995-1000
pubmed: 20970351
Chest. 2000 Apr;117(4):999-1003
pubmed: 10767230
J Biomed Res. 2017 Jan 19;31(3):197-212
pubmed: 28808222
Arch Phys Med Rehabil. 2013 Jan;94(1):53-8
pubmed: 22926460
Eur J Cardiothorac Surg. 2005 Mar;27(3):379-82; discussion 382-3
pubmed: 15740942
Eur J Cardiothorac Surg. 2013 Oct;44(4):e260-5
pubmed: 23892298
J Evid Based Med. 2017 Nov;10(4):255-262
pubmed: 28884946
Thorax. 2015 Mar;70(3):244-50
pubmed: 25323620
Gen Thorac Cardiovasc Surg. 2017 Jul;65(7):388-391
pubmed: 28281043
Eur J Cardiothorac Surg. 2008 Jan;33(1):95-8
pubmed: 18006327
Cancer Manag Res. 2017 Nov 16;9:657-670
pubmed: 29180901
J Thorac Oncol. 2013 Feb;8(2):214-21
pubmed: 23238118
Ann Transl Med. 2019 Oct;7(20):544
pubmed: 31807526
Am J Physiol Lung Cell Mol Physiol. 2005 Apr;288(4):L596-8
pubmed: 15757952
Ann Thorac Surg. 2016 Jun;101(6):2077-84
pubmed: 27021033
Ann Thorac Cardiovasc Surg. 2011;17(5):461-8
pubmed: 21881371
Thorax. 2019 Aug;74(8):787-796
pubmed: 31048509
Respir Med. 2015 Apr;109(4):437-42
pubmed: 25641113
J Thorac Dis. 2017 Jul;9(7):1919-1929
pubmed: 28839990
Int J Chron Obstruct Pulmon Dis. 2016 Oct 07;11:2519-2526
pubmed: 27785008
Eur J Cardiothorac Surg. 2013 Oct;44(4):e266-71
pubmed: 23959742
Stat Med. 2018 May 20;37(11):1874-1894
pubmed: 29508424
Thorax. 2010 Sep;65(9):815-8
pubmed: 20805178
J Surg Res. 2017 Mar;209:30-36
pubmed: 28032568
Thorax. 2013 Jun;68(6):580-5
pubmed: 23429831
Chest. 2000 Nov;118(5):1263-70
pubmed: 11083673
J Thorac Oncol. 2016 Jan;11(1):39-51
pubmed: 26762738
Interact Cardiovasc Thorac Surg. 2016 Sep;23(3):486-97
pubmed: 27226400
J Thorac Dis. 2014 Dec;6(12):1800-7
pubmed: 25589976