Molecular Imaging of Inflammation in Osteoarthritis Using a Water-Soluble Fluorocoxib.


Journal

ACS medicinal chemistry letters
ISSN: 1948-5875
Titre abrégé: ACS Med Chem Lett
Pays: United States
ID NLM: 101521073

Informations de publication

Date de publication:
08 Oct 2020
Historique:
received: 06 11 2019
accepted: 24 02 2020
entrez: 16 10 2020
pubmed: 17 10 2020
medline: 17 10 2020
Statut: epublish

Résumé

Clinical imaging approaches to detect inflammatory biomarkers, such as cyclooxygenase-2 (COX-2), may facilitate the diagnosis and therapy of inflammatory diseases. To this end, we report the discovery of

Identifiants

pubmed: 33062167
doi: 10.1021/acsmedchemlett.9b00512
pmc: PMC7549260
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1875-1880

Subventions

Organisme : NCI NIH HHS
ID : P50 CA236733
Pays : United States
Organisme : NCI NIH HHS
ID : R35 CA197570
Pays : United States
Organisme : NIH HHS
ID : S10 OD021804
Pays : United States

Déclaration de conflit d'intérêts

The authors declare no competing financial interest.

Références

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Auteurs

Md Jashim Uddin (MJ)

A. B. Hancock, Jr. Memorial Laboratory for Cancer Research, Departments of Biochemistry, Chemistry, and Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, United States.

Anoop Vemulapalli (A)

A. B. Hancock, Jr. Memorial Laboratory for Cancer Research, Departments of Biochemistry, Chemistry, and Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, United States.

Hiroaki Niitsu (H)

Department of Medicine, and Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States.

Brenda C Crews (BC)

A. B. Hancock, Jr. Memorial Laboratory for Cancer Research, Departments of Biochemistry, Chemistry, and Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, United States.

Connor G Oltman (CG)

A. B. Hancock, Jr. Memorial Laboratory for Cancer Research, Departments of Biochemistry, Chemistry, and Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, United States.

Philip J Kingsley (PJ)

A. B. Hancock, Jr. Memorial Laboratory for Cancer Research, Departments of Biochemistry, Chemistry, and Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, United States.

Taylor E Kavanaugh (TE)

Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee 37232, United States.

Sean K Bedingfield (SK)

Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee 37232, United States.

J Oliver Mcintyre (JO)

Department of Cancer Biology, Vanderbilt Institute of Imaging Science, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, United States.

Matthew Milad (M)

A. B. Hancock, Jr. Memorial Laboratory for Cancer Research, Departments of Biochemistry, Chemistry, and Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, United States.

Ansari M Aleem (AM)

A. B. Hancock, Jr. Memorial Laboratory for Cancer Research, Departments of Biochemistry, Chemistry, and Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, United States.

Robert J Coffey (RJ)

Department of Medicine, and Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States.

Craig L Duvall (CL)

Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee 37232, United States.

Lawrence J Marnett (LJ)

A. B. Hancock, Jr. Memorial Laboratory for Cancer Research, Departments of Biochemistry, Chemistry, and Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, United States.

Classifications MeSH