Indications and Outcome in Patients Undergoing Left Atrial Appendage Closure-The Austrian LAAC Registry.
atrial fibrillation
bleeding
left atrial appendage
registry
stroke
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
13 Oct 2020
13 Oct 2020
Historique:
received:
21
09
2020
revised:
06
10
2020
accepted:
10
10
2020
entrez:
17
10
2020
pubmed:
18
10
2020
medline:
18
10
2020
Statut:
epublish
Résumé
Complete real-world data on the indications and outcomes of left atrial appendage closure (LAAC) outside of clinical trials are rare. In this study, we stratified patients undergoing LAAC by indication groups. This analysis of the national multicentre Austrian LAAC Registry comprised all patients that underwent LAAC up until 2018 at the currently active centres in Austria. The baseline characteristics, procedural details and outcomes between the following indication groups were compared: bleeding as an indication for LAAC ("bleeding" group) vs. thromboembolism despite oral anticoagulation (OAC; "thromboembolism" group) vs. an intolerance to OAC for reasons other than the above ("other" group). The analysis included 186 patients, with 59.7% in the "bleeding" group, 8.1% in the "thromboembolism" group and 32.2% in the "other" group. The CHADS In routine clinical practice, LAAC was used in a heterogeneous patient population with atrial fibrillation (AF) and contraindication, inefficacy or intolerance to OAC. The long-term outcome was favourable in all groups.
Sections du résumé
BACKGROUND
BACKGROUND
Complete real-world data on the indications and outcomes of left atrial appendage closure (LAAC) outside of clinical trials are rare. In this study, we stratified patients undergoing LAAC by indication groups.
METHODS
METHODS
This analysis of the national multicentre Austrian LAAC Registry comprised all patients that underwent LAAC up until 2018 at the currently active centres in Austria. The baseline characteristics, procedural details and outcomes between the following indication groups were compared: bleeding as an indication for LAAC ("bleeding" group) vs. thromboembolism despite oral anticoagulation (OAC; "thromboembolism" group) vs. an intolerance to OAC for reasons other than the above ("other" group).
RESULTS
RESULTS
The analysis included 186 patients, with 59.7% in the "bleeding" group, 8.1% in the "thromboembolism" group and 32.2% in the "other" group. The CHADS
CONCLUSIONS
CONCLUSIONS
In routine clinical practice, LAAC was used in a heterogeneous patient population with atrial fibrillation (AF) and contraindication, inefficacy or intolerance to OAC. The long-term outcome was favourable in all groups.
Identifiants
pubmed: 33066034
pii: jcm9103274
doi: 10.3390/jcm9103274
pmc: PMC7600032
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Boston Scientific Corporation
ID : (no grant number available)
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