In Vivo Modulation of Angiogenesis and Immune Response on a Collagen Matrix via Extracorporeal Shockwaves.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
14 Oct 2020
Historique:
received: 09 09 2020
revised: 02 10 2020
accepted: 11 10 2020
entrez: 17 10 2020
pubmed: 18 10 2020
medline: 26 2 2021
Statut: epublish

Résumé

The effective management of tissue integration and immunological responses to transplants decisively co-determines the success of soft and hard tissue reconstruction. The aim of this in vivo study was to evaluate the eligibility of extracorporeal shock wave therapy (ESWT) with respect to its ability to modulate angiogenesis and immune response to a collagen matrix (CM) for tissue engineering in the chorioallantoic membrane (CAM) assay, which is performed with fertilized chicken eggs. CM were placed on the CAM on embryonic development day (EDD) 7; at EDD-10, ESWT was conducted at 0.12 mJ/mm

Identifiants

pubmed: 33066403
pii: ijms21207574
doi: 10.3390/ijms21207574
pmc: PMC7589066
pii:
doi:

Substances chimiques

Avian Proteins 0
Hypoxia-Inducible Factor 1, alpha Subunit 0
Vascular Endothelial Growth Factor A 0
Collagen 9007-34-5
Nitric Oxide Synthase Type II EC 1.14.13.39
Matrix Metalloproteinases EC 3.4.24.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Diana Heimes (D)

Department of Oral- and Maxillofacial and Plastic Surgery, University Medical Center Mainz, Augustusplatz 2, 55131 Mainz, Germany.

Nadine Wiesmann (N)

Department of Oral- and Maxillofacial and Plastic Surgery, University Medical Center Mainz, Augustusplatz 2, 55131 Mainz, Germany.
Molecular Tumor Biology, Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center of the Johannes Gutenberg University, Langenbeckstraße 1, 55131 Mainz, Germany.

Jonas Eckrich (J)

Molecular Tumor Biology, Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center of the Johannes Gutenberg University, Langenbeckstraße 1, 55131 Mainz, Germany.

Juergen Brieger (J)

Molecular Tumor Biology, Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center of the Johannes Gutenberg University, Langenbeckstraße 1, 55131 Mainz, Germany.

Stefan Mattyasovszky (S)

Department of Orthopedics and Traumatology, University Medical Center of the Johannes Gutenberg University of Mainz, Langenbeckstraße 1, 55131 Mainz, Germany.

Peter Proff (P)

Department of Orthodontics, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany.

Manuel Weber (M)

Department of Oral and Maxillofacial Surgery, Friedrich-Alexander University Erlangen-Nürnberg, 91054 Erlangen, Germany.

James Deschner (J)

Department of Periodontology and Operative Dentistry, University Medical Center of the Johannes Gutenberg University, Augustusplatz 2, 55131 Mainz, Germany.

Bilal Al-Nawas (B)

Department of Oral- and Maxillofacial and Plastic Surgery, University Medical Center Mainz, Augustusplatz 2, 55131 Mainz, Germany.

Peer W Kämmerer (PW)

Department of Oral- and Maxillofacial and Plastic Surgery, University Medical Center Mainz, Augustusplatz 2, 55131 Mainz, Germany.

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Classifications MeSH