Prevalence of genital HPV infection in STI and healthy populations and risk factors for viral persistence.
Human papillomavirus prevalence
Persistence
Risk factors
Journal
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
ISSN: 1435-4373
Titre abrégé: Eur J Clin Microbiol Infect Dis
Pays: Germany
ID NLM: 8804297
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
received:
20
04
2020
accepted:
14
10
2020
pubmed:
18
10
2020
medline:
14
8
2021
entrez:
17
10
2020
Statut:
ppublish
Résumé
Human papillomavirus (HPV) is a well-established carcinogenic agent. This study aimed to assess prevalence and persistence rate of genital HPV infection in sexually transmitted infections (STIs) patients and healthy subjects. The risk factors influencing the persistence of genital HPV infection were also investigated. The samples were collected with the ThinPrep liquid-based cytology system. Among the HPV-positive patients, those consenting were retested after 12 months. Overall, 145/292 subjects proved HPV positive with a higher prevalence (51%) in STI than in healthy population (43%). The persistence of genital HPV infection was statistically associated with female gender, HR-HPV infection, smoking, and Ureaplasma parvum infection.
Identifiants
pubmed: 33067736
doi: 10.1007/s10096-020-04073-6
pii: 10.1007/s10096-020-04073-6
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
885-888Références
Forman D, de Martel C, Lacey CJ et al (2012) Global burden of human papillomavirus and related diseases. Vaccine 30(Suppl 5):F12–F23. https://doi.org/10.1016/j.vaccine.2012.07.055
doi: 10.1016/j.vaccine.2012.07.055
pubmed: 23199955
Moscicki AB, Schiffman M, Burchell A et al (2012) Updating the natural history of human papillomavirus and anogenital cancers. Vaccine 30(Suppl 5):F24–F33. https://doi.org/10.1016/j.vaccine.2012.05.089
doi: 10.1016/j.vaccine.2012.05.089
pubmed: 23199964
pmcid: 3700362
Broccolo F, Ciccarese G, Rossi A et al (2018) Human papillomavirus (HPV) and Epstein-Barr virus (EBV) in keratinizing versus non- keratinizing squamous cell carcinoma of the oropharynx. Infect Agent Cancer 13:32. https://doi.org/10.1186/s13027-018-0205-6
doi: 10.1186/s13027-018-0205-6
pubmed: 30455727
pmcid: 6230228
Ghittoni R, Accardi R, Chiocca S et al (2015) Role of human papillomaviruses in carcinogenesis. Ecancermedicalscience 9:526–535. https://doi.org/10.3332/ecancer.2015.526
doi: 10.3332/ecancer.2015.526
pubmed: 25987895
pmcid: 4431404
Cossellu G, Fedele L, Badaoui B et al (2018) Prevalence and concordance of oral and genital HPV in women positive for cervical HPV infection and in their sexual stable partners: an Italian screening study. PLoS One 13:e0205574. https://doi.org/10.1371/journal.pone.0205574
doi: 10.1371/journal.pone.0205574
pubmed: 30335788
pmcid: 6193646
Moscicki AB, Shiboski S, Hills NK et al (2004) Regression of low-grade squamous intra-epithelial lesions in young women. Lancet 364:1678–1683
doi: 10.1016/S0140-6736(04)17354-6
Drago F, Herzum A, Ciccarese G et al (2016) Ureaplasma parvum as a possible enhancer agent of HPV-induced cervical intraepithelial neoplasia: preliminary results. J Med Virol 88:2023–2024. https://doi.org/10.1002/jmv.24583
doi: 10.1002/jmv.24583
pubmed: 27219674
Deshmukh AA, Tanner RJ, Luetke MC et al (2017) Prevalence and risk of penile human papillomavirus infection: evidence from the national health and nutrition examination survey 2013-2014. Clin Infect Dis 64:1360–1366. https://doi.org/10.1093/cid/cix159
doi: 10.1093/cid/cix159
pubmed: 28205678
Steinau M, Hariri S, Gillison ML et al (2014) Prevalence of cervical and oral human papillomavirus infections among US women. J Infect Dis 209:1739–1743. https://doi.org/10.1093/infdis/jit799
doi: 10.1093/infdis/jit799
pubmed: 24319284
Sehnal B, Zikan M, Nipcova M et al (2019) The association among cervical, anal, and oral HPV infections in high-risk and low-risk women. Eur J Obstet Gynecol Reprod Biol X 4:100061. https://doi.org/10.1016/j.eurox.2019.100061
doi: 10.1016/j.eurox.2019.100061
pubmed: 31517298
pmcid: 6728742
Ciccarese G, Herzum A, Rebora A et al (2017) Prevalence of genital, oral, and anal HPV infection among STI patients in Italy. J Med Virol 89:1121–1124. https://doi.org/10.1002/jmv.24746
doi: 10.1002/jmv.24746
pubmed: 27935070
Fu T-CF, Carter JJ, Hughes JP et al (2016) Re-detection versus new acquisition of high-risk human papillomavirus in mid-adult women. Int J Cancer 139:2201–2212. https://doi.org/10.1002/ijc.30283
doi: 10.1002/ijc.30283
pubmed: 27448488
pmcid: 5222584
Kero K, Rautava J, Syrjänen K et al (2014) Smoking increases oral HPV persistence among men: 7-year follow-up study. Eur J Clin Microbiol Infect Dis 33:123–133
doi: 10.1007/s10096-013-1938-1
Giarrè M, Caldeira S, Malanchi I et al (2001) Induction of pRb degradation by the human papillomavirus type 16 E7 protein is essential to efficiently overcome p16INK4a-imposed G1 cell cycle arrest. J Virol 75:4705–4712
doi: 10.1128/JVI.75.10.4705-4712.2001
Guleria C, Suri V, Kapoor R et al (2019) Human papillomavirus 16 infection alters the toll-like receptors and downstream signaling cascade: a plausible early event in cervical squamous cell carcinoma development. Gynecol Oncol 155:151–160. https://doi.org/10.1016/j.ygyno.2019.07.023
doi: 10.1016/j.ygyno.2019.07.023
pubmed: 31375269
Deacon JM, Evans CD, Yule R et al (2000) Sexual behaviour and smoking as determinants of cervical HPV infection and of CIN3 among those infected: a case-control study nested within the Manchester cohort. Br J Cancer 83:1565–1572
doi: 10.1054/bjoc.2000.1523
Moore TO, Moore AY, Carrasco D et al (2001) Human papillomavirus, smoking, and cancer. J Cutan Med Surg 5:323–328
doi: 10.1177/120347540100500408
Arokiyaraj S, Seo SS, Kwon M et al (2018) Association of cervical microbial community with persistence, clearance and negativity of human papillomavirus in Korean women: a longitudinal study. Sci Rep 8:15479. https://doi.org/10.1038/s41598-018-33750-y
doi: 10.1038/s41598-018-33750-y
pubmed: 30341386
pmcid: 6195586
Ritu W, Enqi W, Zheng S et al (2019) Evaluation of the associations between cervical microbiota and HPV infection, clearance, and persistence in cytologically normal women. Cancer Prev Res (Phila) 12:43–56. https://doi.org/10.1158/1940-6207.CAPR-18-0233
doi: 10.1158/1940-6207.CAPR-18-0233
Ho GY, Bierman R, Beardsley L et al (1998) Natural history of cervicovaginal papillomavirus infection in young women. N Engl J Med 338:423–428
doi: 10.1056/NEJM199802123380703
Oyervides-Muñoz MA, Pérez-Maya AA, Sánchez-Domínguez CN et al (2020) Multiple HPV infections and viral load association in persistent cervical lesions in Mexican women. Viruses 12:380
doi: 10.3390/v12040380
van der Weele P, van Logchem E, Wolffs P et al (2016) Correlation between viral load, multiplicity of infection, and persistence of HPV16 and HPV18 infection in a Dutch cohort of young women. J Clin Virol 83:6–11
doi: 10.1016/j.jcv.2016.07.020
Quint W, Jenkins D, Molijn A et al (2012) One virus, one lesion--individual components of CIN lesions contain a specific HPV type. J Pathol 227:62–71
doi: 10.1002/path.3970