Cervical myelopathy caused by ventrally located atlanto-axial synovial cysts: An open quest for the safest and most effective surgical management. Case series and systematic review of the literature.


Journal

Neuro-Chirurgie
ISSN: 1773-0619
Titre abrégé: Neurochirurgie
Pays: France
ID NLM: 0401057

Informations de publication

Date de publication:
Dec 2020
Historique:
received: 12 05 2020
revised: 31 08 2020
accepted: 08 09 2020
pubmed: 18 10 2020
medline: 23 6 2021
entrez: 17 10 2020
Statut: ppublish

Résumé

Despite a good understanding of the natural history of spinal synovial cysts (SCs), a widespread agreement regarding their optimal management is still lacking. This is particularly true for SCs occurring at the C1-C2 level, which are rare, but oftentimes lead to a rapidly evolving cervical myelopathy. We report a series of 4 patients (M:F ratio=1:1; mean age 63.5 years) presenting with progressive cervical myelopathy secondary to ventrally located C1-C2 SCs. All patients underwent a postero-lateral facet-sparing intradural approach with total excision of the SCs. Functional status was assessed pre- and postoperatively with Nurick scale and the modified Japanese Orthopaedic association grading. Furthermore we conducted a systematic review, following PRISMA guidelines of pertinent literature to contextualize the options for surgical management of such lesions. Complete excision of the SCs was confirmed radiologically and on histological analysis. All measures of functional status improved post-operatively, and no cyst recurrence or need for instrumented fusion were noted during follow up (range from 22 to 88 months). Our experience suggests that the facet-sparing intradural approach provides excellent clinical outcomes without causing any C1-C2 instability. This is in keeping with the take home message emerging from our literature review, which confirms that treatment should aim at radical resection of SCs while minimizing the risk of postoperative instability.

Sections du résumé

OF BACKGROUND DATA BACKGROUND
Despite a good understanding of the natural history of spinal synovial cysts (SCs), a widespread agreement regarding their optimal management is still lacking. This is particularly true for SCs occurring at the C1-C2 level, which are rare, but oftentimes lead to a rapidly evolving cervical myelopathy.
METHODS METHODS
We report a series of 4 patients (M:F ratio=1:1; mean age 63.5 years) presenting with progressive cervical myelopathy secondary to ventrally located C1-C2 SCs. All patients underwent a postero-lateral facet-sparing intradural approach with total excision of the SCs. Functional status was assessed pre- and postoperatively with Nurick scale and the modified Japanese Orthopaedic association grading. Furthermore we conducted a systematic review, following PRISMA guidelines of pertinent literature to contextualize the options for surgical management of such lesions.
RESULTS RESULTS
Complete excision of the SCs was confirmed radiologically and on histological analysis. All measures of functional status improved post-operatively, and no cyst recurrence or need for instrumented fusion were noted during follow up (range from 22 to 88 months).
CONCLUSION CONCLUSIONS
Our experience suggests that the facet-sparing intradural approach provides excellent clinical outcomes without causing any C1-C2 instability. This is in keeping with the take home message emerging from our literature review, which confirms that treatment should aim at radical resection of SCs while minimizing the risk of postoperative instability.

Identifiants

pubmed: 33068595
pii: S0028-3770(20)30433-1
doi: 10.1016/j.neuchi.2020.09.007
pii:
doi:

Types de publication

Case Reports Journal Article Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

447-454

Informations de copyright

Copyright © 2020 Elsevier Masson SAS. All rights reserved.

Auteurs

S Chibbaro (S)

Department of Neurosurgery, Strasbourg University Hospital, Strasbourg, France; Department of Neurosurgery, Lariboisiere University Hospital, Paris, France.

A Gubian (A)

Department of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.

I Zaed (I)

Department of Neurosurgery, Strasbourg University Hospital, Strasbourg, France. Electronic address: ismailzaed1@gmail.com.

F Hajhouji (F)

Department of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.

R Pop (R)

Interventional Neuroradiology Unit, Strasbourg University Hospital, Strasbourg, France.

J Todeschi (J)

Department of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.

G Bernard (G)

Department of Neurosurgery, Lariboisiere University Hospital, Paris, France.

P Di Emidio (P)

Department of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.

C-H Mallereau (CH)

Department of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.

F Proust (F)

Department of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.

M Ganau (M)

Department of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.

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Classifications MeSH