Rhinoscopic Appearance and Clinical Features of a Nasal Transmissible Venereal Tumor in a Dog.
PCR
TVT
canine
neoplasia
vincristine
Journal
Topics in companion animal medicine
ISSN: 1946-9837
Titre abrégé: Top Companion Anim Med
Pays: United States
ID NLM: 101465592
Informations de publication
Date de publication:
Mar 2021
Mar 2021
Historique:
received:
10
09
2020
revised:
19
09
2020
accepted:
12
10
2020
pubmed:
19
10
2020
medline:
13
10
2021
entrez:
18
10
2020
Statut:
ppublish
Résumé
A 2-year-old male neutered mixed breed dog was referred for evaluation of left-sided unilateral epistaxis and mucoid discharge following adoption from Mexico 2 months prior to presentation. Computed tomography (CT) showed soft tissue that filled the entirety of the left nasal passage with mild turbinate loss. Subsequent rhinoscopy revealed multifocal patches of discrete, white, wispy, vascularized abnormal tissue in the left nasal cavity. Cytology and histopathology procured with rhinoscopic-guidance were suspicious for transmissible venereal tumor (TVT). Confirmation of a TVT diagnosis was made with polymerase chain reaction for the long interspersed element inserted upstream of the c-myc gene. The dog was treated with 4 cycles of vincristine (0.5 mg/m
Identifiants
pubmed: 33069901
pii: S1938-9736(20)30074-X
doi: 10.1016/j.tcam.2020.100476
pii:
doi:
Substances chimiques
Antineoplastic Agents, Phytogenic
0
Vincristine
5J49Q6B70F
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
100476Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.