Activation of Nell-1 in BMSC Sheet Promotes Implant Osseointegration Through Regulating Runx2/Osterix Axis.
NELL-1
OPG-RANKL axis
Osterix
Runx2
cell sheet and tissue engineering
implant osseointegration
Journal
Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250
Informations de publication
Date de publication:
2020
2020
Historique:
received:
08
05
2020
accepted:
11
08
2020
entrez:
19
10
2020
pubmed:
20
10
2020
medline:
20
10
2020
Statut:
epublish
Résumé
Neural epidermal growth factor-like 1 protein (Nell-1) is first studied because of its association with human craniosynostosis. Nell-1 has been used to accelerate the process of fracture healing because of the osteoinductive ability in recent years. However, the role of Nell-1 during the process of osteointegration is unknown. Here we show that activation of Nell-1 in the BMSC sheet promotes osseointegration
Identifiants
pubmed: 33072736
doi: 10.3389/fcell.2020.00868
pmc: PMC7536315
doi:
Types de publication
Journal Article
Langues
eng
Pagination
868Informations de copyright
Copyright © 2020 Lai, Xi, Du, Jiang, Li, Huang, Miao, Wang, Wang and Yang.
Références
Am J Pathol. 2016 Feb;186(2):419-34
pubmed: 26772960
ACS Nano. 2018 Aug 28;12(8):7883-7891
pubmed: 29979574
J Orthop Sci. 2013 Jul;18(4):646-57
pubmed: 23686083
J Bone Miner Res. 2011 Apr;26(4):777-91
pubmed: 20939017
Biomaterials. 2013 Jan;34(1):11-8
pubmed: 23069710
J Biomed Mater Res A. 2009 Jul;90(1):175-85
pubmed: 18491389
Hum Mol Genet. 2006 Apr 15;15(8):1329-41
pubmed: 16537572
Tissue Eng Part A. 2018 Jul;24(13-14):1112-1124
pubmed: 29343182
J Bone Miner Res. 1999 Jan;14(1):80-9
pubmed: 9893069
Mol Ther. 2007 Oct;15(10):1872-80
pubmed: 17653100
PLoS One. 2011;6(9):e24638
pubmed: 21931789
Tissue Eng Part A. 2013 Nov;19(21-22):2390-401
pubmed: 23758588
Biomaterials. 2014 Aug;35(24):6614-21
pubmed: 24818884
Am J Pathol. 2017 May;187(5):963-972
pubmed: 28302495
Exp Ther Med. 2017 Dec;14(6):5717-5726
pubmed: 29250137
Colloids Surf B Biointerfaces. 2018 Apr 1;164:58-69
pubmed: 29413621
Theranostics. 2017 Jun 25;7(9):2509-2523
pubmed: 28744331
Tissue Eng Part A. 2018 Feb;24(3-4):207-218
pubmed: 28463604
Acta Biomater. 2014 Jul;10(7):3145-55
pubmed: 24650971
Am J Pathol. 2006 Sep;169(3):903-15
pubmed: 16936265
Stem Cells. 2015 Mar;33(3):904-15
pubmed: 25376942
Bone. 2011 Mar 1;48(3):485-95
pubmed: 20959151
Chin Med J (Engl). 2009 Apr 20;122(8):972-9
pubmed: 19493425
J Control Release. 2006 Nov 28;116(2):193-203
pubmed: 16890320
Exp Hematol. 2006 Nov;34(11):1606-7
pubmed: 17046584
Biomaterials. 2020 Jan;226:119541
pubmed: 31634652
Clin Implant Dent Relat Res. 2017 Dec;19(6):1074-1081
pubmed: 29052336
J Clin Invest. 2002 Sep;110(6):861-70
pubmed: 12235118
Nanomedicine. 2020 Feb;24:102129
pubmed: 31760162
Prog Retin Eye Res. 2015 Jul;47:38-63
pubmed: 25645519
Acta Biomater. 2014 Dec;10(12):5128-5138
pubmed: 25220281
Genes Dis. 2017 Sep;4(3):127-137
pubmed: 29276737
Endocrinol Metab (Seoul). 2015 Mar 27;30(1):35-44
pubmed: 25827455
J Bone Miner Res. 2007 Jan;22(1):7-18
pubmed: 17042739
Am J Pathol. 2018 Feb;188(2):392-403
pubmed: 29137952