Newborn Screening for Sickle Cell Disease in Europe.

newborn screening sickle cell disease

Journal

International journal of neonatal screening
ISSN: 2409-515X
Titre abrégé: Int J Neonatal Screen
Pays: Switzerland
ID NLM: 101665400

Informations de publication

Date de publication:
Mar 2019
Historique:
received: 30 12 2018
accepted: 06 02 2019
entrez: 19 10 2020
pubmed: 12 2 2019
medline: 12 2 2019
Statut: epublish

Résumé

The history of newborn screening (NBS) for sickle cell disease (SCD) in Europe goes back almost 40 years. However, most European countries have not established it to date. The European screening map is surprisingly heterogenous. The first countries to introduce sickle cell screening on a national scale were France and England. The French West Indies started to screen their newborns for SCD as early as 1983/84. To this day, all countries of the United Kingdom of Great Britain and Northern Ireland have added SCD as a target disease to their NBS programs. The Netherlands, Spain and Malta also have national programs. Belgium screens regionally in the Brussels and Liège regions, Ireland has been running a pilot for many years that has become quasi-official. However, the Belgian and Irish programs are not publicly funded. Italy and Germany have completed several pilot studies but are still in the preparatory phase of national NBS programs for SCD, although both countries have well-established concepts for metabolic and endocrine disorders. This article will give a brief overview of the situation in Europe and put a focus on the programs of the two pioneers of the continent, England and France.

Identifiants

pubmed: 33072975
doi: 10.3390/ijns5010015
pii: IJNS-05-00015
pmc: PMC7510219
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

15

Informations de copyright

© 2019 by the authors.

Déclaration de conflit d'intérêts

Conflicts of InterestThe authors declare no conflict of interest.

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Auteurs

Yvonne Daniel (Y)

Public Health England, NHS Sickle Cell and Thalassemia Screening Programme, London SE16LH, UK.

Jacques Elion (J)

Laboratoire d'Excellence GR-Ex, UMR_S1134, Inserm, Université Paris Diderot, Sorbonne Paris Cité, Institut National de la Transfusion Sanguine, 75015 Paris, France.

Bichr Allaf (B)

NBS Laboratory for Haemoglobinopathies, Hôpital Universitaire Robert-Debré, 75019 Paris, France.

Catherine Badens (C)

Département de génétique médicale, Aix-Marseille Université, Hôpital de la Timone, 13385 Marseille, France.

Marelle J Bouva (MJ)

National Institute for Public Health and the Environment, Centre for Health Protection, 3720 Bilthoven, The Netherlands.

Ian Brincat (I)

Pediatric Medicine Laboratory, Department of Pathology, Mater Dei Hospital, Triq Tal-Qroqq, MSD2090 Msida, Malta.

Elena Cela (E)

Department of Pediatric Oncology/Hematology, Hospital Universitario General Gregorio Marañón, Facultad de Medicina, Universidad Complutense Madrid, 28007 Madrid, Spain.

Cathy Coppinger (C)

Public Health England, NHS Sickle Cell and Thalassemia Screening Programme, London SE16LH, UK.

Mariane de Montalembert (M)

Department of Pediatrics, Reference Center for Sickle Cell Disease, AP-HP Hôpital Universitaire Necker-Enfants Malades, 75743 Paris, France.

Béatrice Gulbis (B)

Department of Clinical Chemistry, Cliniques Universitaires de Bruxelles, Hôpital Erasme-ULB, 1070 Bruxelles, Belgium.

Joan Henthorn (J)

Public Health England, NHS Sickle Cell and Thalassemia Screening Programme, London SE16LH, UK.

Olivier Ketelslegers (O)

Laboratoire-Biologie Clinique, Centre Hospitalier Régional de la Citadelle, 4000 Liège, Belgium.

Corrina McMahon (C)

Our Lady's Children's Hospital, Crumlin, D12V004 Dublin, Ireland.

Allison Streetly (A)

School of Population Health and Environmental Sciences, Faculty of Life Sciences & Medicine, King's College London, London WC2R2LS, UK.
Division of Healthcare Public Health, Health Protection and Medical Directorate, Public Health England, London SE18UG, UK.

Raffaella Colombatti (R)

Department of Child and Maternal Health, Clinic of Pediatric Hematology/Oncology, Azienda Ospedaliera-Università di Padova, 35129 Padova, Italy.

Stephan Lobitz (S)

Department of Pediatric Oncology/Hematology, Kinderkrankenhaus Amsterdamer Straße, 50735 Cologne, Germany.

Classifications MeSH