Role of the Helix-8 and C-Terminal Tail in Regulating Proteinase Activated Receptor 2 Signaling.


Journal

ACS pharmacology & translational science
ISSN: 2575-9108
Titre abrégé: ACS Pharmacol Transl Sci
Pays: United States
ID NLM: 101721411

Informations de publication

Date de publication:
09 Oct 2020
Historique:
received: 29 04 2020
entrez: 19 10 2020
pubmed: 20 10 2020
medline: 20 10 2020
Statut: epublish

Résumé

The C-terminal tail of G-protein-coupled receptors (GPCR) contain important regulatory sites that enable interaction with intracellular signaling effectors. Here we examine the relative contribution of the C-tail serine/threonine phosphorylation sites (Ser

Identifiants

pubmed: 33073187
doi: 10.1021/acsptsci.0c00039
pmc: PMC7551709
doi:

Types de publication

Journal Article

Langues

eng

Pagination

868-882

Déclaration de conflit d'intérêts

The authors declare no competing financial interest.

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Auteurs

Pierre E Thibeault (PE)

Department of Physiology and Pharmacology, University of Western Ontario, 1151 Richmond Street, London, Ontario N6A5C1, Canada.

Rithwik Ramachandran (R)

Department of Physiology and Pharmacology, University of Western Ontario, 1151 Richmond Street, London, Ontario N6A5C1, Canada.

Classifications MeSH