Pain Intensity as a Lagging Indicator of Patient Improvement: Longitudinal Relationships With Sleep, Psychiatric Distress, and Function in Multidisciplinary Care.
Adult
Anxiety
/ epidemiology
Chronic Pain
/ epidemiology
Comorbidity
Depression
/ epidemiology
Humans
Longitudinal Studies
Models, Theoretical
Outcome Assessment, Health Care
Pain Management
Psychosocial Functioning
Retrospective Studies
Severity of Illness Index
Sleep Wake Disorders
/ epidemiology
Stress Disorders, Post-Traumatic
/ epidemiology
Chronic pain
anxiety
depression
disability
post-traumatic stress disorder
sleep disturbance
Journal
The journal of pain
ISSN: 1528-8447
Titre abrégé: J Pain
Pays: United States
ID NLM: 100898657
Informations de publication
Date de publication:
03 2021
03 2021
Historique:
received:
17
08
2020
accepted:
12
10
2020
pubmed:
20
10
2020
medline:
15
12
2021
entrez:
19
10
2020
Statut:
ppublish
Résumé
Despite a common assumption that reductions in chronic pain intensity must precede improvements in other pain-relevant domains, there has been limited empirical inquiry into the temporal ordering of improvements in chronic pain treatment. Cross-lagged models using retrospective clinical data examined relationships between average pain intensity and symptoms of psychological distress, difficulties with sleep initiation and maintenance, and disability in 666 treatment-seeking patients with chronic pain who demonstrated improvement in pain intensity (≥1-point reduction on 0-10 numeric rating scale) over a 1-year span. Results indicated that decreased difficulties with sleep initiation, depressive and anxious symptoms, and disability predicted later improvement in pain intensity, whereas greater pain intensity predicted only later difficulties in sleep initiation and maintenance. A combined lagged model highlighted fewer baseline symptoms of post-traumatic stress disorder and lower levels of baseline disability as significant predictors of later improvements in pain. Overall, our results indicate that reductions in pain intensity may not be the first factors to change in effective chronic pain management. The current findings should be replicated using prospective studies utilizing structured approaches to maximize data capture, as well as uniform interventional approaches to permit greater inferences regarding causal and temporal aspects of the model. PERSPECTIVE: This study demonstrates that pain intensity scores are not robust predictors of psychosocial outcomes longitudinally. Instead, other factors such as sleep initiation, psychological distress and disability appear to be important targets for intervention that may promote effective pain reduction.
Identifiants
pubmed: 33075490
pii: S1526-5900(20)30085-7
doi: 10.1016/j.jpain.2020.10.001
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
313-321Informations de copyright
Copyright © 2020 United States Association for the Study of Pain, Inc. Published by Elsevier Inc. All rights reserved.