Intrapulmonary Pharmacokinetics of Cefepime and Enmetazobactam in Healthy Volunteers: Towards New Treatments for Nosocomial Pneumonia.
ESBL
Monte Carlo simulation
beta-lactams
cefepime
enmetazobactam
pneumonia
population pharmacokinetics
Journal
Antimicrobial agents and chemotherapy
ISSN: 1098-6596
Titre abrégé: Antimicrob Agents Chemother
Pays: United States
ID NLM: 0315061
Informations de publication
Date de publication:
16 12 2020
16 12 2020
Historique:
received:
10
07
2020
accepted:
13
10
2020
pubmed:
21
10
2020
medline:
22
6
2021
entrez:
20
10
2020
Statut:
epublish
Résumé
Cefepime-enmetazobactam is a novel β-lactam-β-lactamase inhibitor combination with broad-spectrum antimicrobial activity against a range of multidrug-resistant
Identifiants
pubmed: 33077666
pii: AAC.01468-20
doi: 10.1128/AAC.01468-20
pmc: PMC7927813
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Azabicyclo Compounds
0
Cephalosporins
0
Triazoles
0
Cefepime
807PW4VQE3
enmetazobactam
80VUN7L00C
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Wellcome Trust
Pays : United Kingdom
Informations de copyright
Copyright © 2020 American Society for Microbiology.
Références
Curr Opin Pharmacol. 2017 Oct;36:114-123
pubmed: 29096171
Antimicrob Agents Chemother. 2015 May;59(5):2688-94
pubmed: 25712356
Crit Care Med. 2003 Aug;31(8):2102-6
pubmed: 12973166
Ther Drug Monit. 2012 Aug;34(4):467-76
pubmed: 22722776
Intensive Care Med. 2004 May;30(5):989-91
pubmed: 14985960
Antimicrob Agents Chemother. 1985 Feb;27(2):207-16
pubmed: 3885849
Expert Opin Pharmacother. 2016;17(7):953-67
pubmed: 26891857
Antibiotics (Basel). 2020 Feb 05;9(2):
pubmed: 32033322
Antimicrob Agents Chemother. 2020 May 21;64(6):
pubmed: 32253209
JAMA. 2018 Sep 11;320(10):984-994
pubmed: 30208454
Antimicrob Agents Chemother. 1987 Jan;31(1):55-9
pubmed: 3566239
Antimicrob Agents Chemother. 2020 May 21;64(6):
pubmed: 32253212
J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Feb 15;917-918:24-9
pubmed: 23353811
Lancet Infect Dis. 2019 Dec;19(12):1299-1311
pubmed: 31563344
J Infect Dis. 2005 Jun 15;191(12):2149-52
pubmed: 15898002
Antimicrob Agents Chemother. 2019 Jun 24;63(7):
pubmed: 30988152
Eur J Clin Pharmacol. 2020 Mar;76(3):349-361
pubmed: 31836928
J Antimicrob Chemother. 2018 May 1;73(5):1340-1347
pubmed: 29385448
Antimicrob Agents Chemother. 2015 Nov 02;60(1):368-75
pubmed: 26525790
Antimicrob Agents Chemother. 2016 Nov 21;60(12):7272-7279
pubmed: 27671063
Antimicrob Agents Chemother. 2019 Apr 25;63(5):
pubmed: 30858223