COVID-19 in a patient with a flare of systemic lupus erythematosus: A rare case-report.
Acute respiratory failure
COVID-19
End-stage kidney disease
Hydroxychloroquine
Steroid therapy
Systemic lupus erythematosus
Journal
Respiratory medicine case reports
ISSN: 2213-0071
Titre abrégé: Respir Med Case Rep
Pays: England
ID NLM: 101604463
Informations de publication
Date de publication:
2020
2020
Historique:
received:
01
07
2020
revised:
29
08
2020
accepted:
07
10
2020
pubmed:
21
10
2020
medline:
21
10
2020
entrez:
20
10
2020
Statut:
ppublish
Résumé
This is a rare case-report of a young female with systemic lupus erythematosus and end-stage kidney disease (on maintenance hemodialysis) who was admitted to our intensive care unit due to life-threatening COVID-19. The patient was diagnosed with a flare of lupus; while being on maintenance hydroxychloroquine therapy. However, after the administration of steroids she made an uneventful recovery and was discharged home. In this report, the diagnostic dilemmas and the therapeutic challenges due to the overlapping clinical, imaging, and laboratory findings between lupus and COVID-19 pneumonitis are outlined. In conclusion, patients with lupus may be affected by COVID-19 despite the administration of hydroxychloroquine. The administration of steroids may have a beneficial effect on mitigating both the flare of SLE and the COVID-19 associated hyperinflammation.
Identifiants
pubmed: 33078093
doi: 10.1016/j.rmcr.2020.101252
pii: S2213-0071(20)30466-4
pmc: PMC7557168
doi:
Types de publication
Case Reports
Langues
eng
Pagination
101252Informations de copyright
© 2020 The Author(s).
Déclaration de conflit d'intérêts
None.
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