An Open Resource for Non-human Primate Optogenetics.

Animals Brain Neurons Neurosciences Optogenetics / methods Primates
Gene therapy Monkey Monkeys Non-human primates Nonhuman primates Open Science Optical control Optogenetic Optogenetics Viral vectors

Journal

Neuron
ISSN: 1097-4199
Titre abrégé: Neuron
Pays: United States
ID NLM: 8809320

Informations de publication

Date de publication:
23 12 2020
Historique:
received: 30 04 2020
revised: 28 07 2020
accepted: 21 09 2020
pubmed: 21 10 2020
medline: 3 2 2021
entrez: 20 10 2020
Statut: ppublish

Résumé

Optogenetics has revolutionized neuroscience in small laboratory animals, but its effect on animal models more closely related to humans, such as non-human primates (NHPs), has been mixed. To make evidence-based decisions in primate optogenetics, the scientific community would benefit from a centralized database listing all attempts, successful and unsuccessful, of using optogenetics in the primate brain. We contacted members of the community to ask for their contributions to an open science initiative. As of this writing, 45 laboratories around the world contributed more than 1,000 injection experiments, including precise details regarding their methods and outcomes. Of those entries, more than half had not been published. The resource is free for everyone to consult and contribute to on the Open Science Framework website. Here we review some of the insights from this initial release of the database and discuss methodological considerations to improve the success of optogenetic experiments in NHPs.

Identifiants

DOI: 10.1016/j.neuron.2020.09.027 PMID: 33080229 PMC: PMC7962465
pubmed: 33080229
pii: S0896-6273(20)30751-0
doi: 10.1016/j.neuron.2020.09.027
pmc: PMC7962465
mid: NIHMS1670678
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, N.I.H., Intramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

1075-1090.e6

Subventions

Organisme : NIMH NIH HHS
ID : P50 MH094258
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS078127
Pays : United States
Organisme : Wellcome Trust
ID : 095495
Pays : United Kingdom
Organisme : NEI NIH HHS
ID : R00 EY029374
Pays : United States
Organisme : NINDS NIH HHS
ID : U01 NS099702
Pays : United States
Organisme : Howard Hughes Medical Institute
Pays : United States
Organisme : Medical Research Council
Pays : United Kingdom
Organisme : Intramural NIH HHS
ID : ZIA MH002958
Pays : United States
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : NEI NIH HHS
ID : R21 EY022853
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY016454
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH110594
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY026156
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY019743
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH116937
Pays : United States
Organisme : NIH HHS
ID : P51 OD011132
Pays : United States
Organisme : Intramural NIH HHS
ID : ZIA EY000415
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY031959
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY005911
Pays : United States
Organisme : NIMH NIH HHS
ID : U01 MH109146
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY011378
Pays : United States
Organisme : NIDCR NIH HHS
ID : R01 DE013962
Pays : United States
Organisme : NINDS NIH HHS
ID : U01 NS099720
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY029666
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS093998
Pays : United States
Organisme : NEI NIH HHS
ID : R21 EY024516
Pays : United States
Organisme : NEI NIH HHS
ID : K99 EY029374
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY026812
Pays : United States
Organisme : NEI NIH HHS
ID : R21 EY026240
Pays : United States
Organisme : NINDS NIH HHS
ID : P50 NS098685
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH108627
Pays : United States
Organisme : NEI NIH HHS
ID : P30 EY014800
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY014681
Pays : United States
Organisme : NICHD NIH HHS
ID : DP1 HD075623
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY013692
Pays : United States

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Interests S. Palfi received consulting honorarium from OxfordBiomedica. K.V.S. is a consultant for Neuralink and is on the scientific advisory board for CTRL-Labs, MIND-X, Inscopix, and Heal. These entities did not support this work. P.N.S. has financial interests in Neuralink, a company developing clinical therapies using brain stimulation.

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Auteurs

Sébastien Tremblay (S)

Department of Neuroscience, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: strem@pennmedicine.upenn.edu.

Leah Acker (L)

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Arash Afraz (A)

National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA.

Daniel L Albaugh (DL)

Yerkes National Primate Research Center, Morris K. Udall Center of Excellence for Parkinson's Disease, Department of Neurology, Emory University, GA 30329, USA.

Hidetoshi Amita (H)

Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Ariana R Andrei (AR)

Department of Neurobiology and Anatomy, McGovern Medical School, University of Texas-Houston, Houston, TX 77030, USA.

Alessandra Angelucci (A)

Department of Ophthalmology, Moran Eye Institute, University of Utah, Salt Lake City, UT 84132, USA.

Amir Aschner (A)

Dominik P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

Puiu F Balan (PF)

Laboratory of Neuro- and Psychophysiology, KU Leuven, 3000 Leuven, Belgium.

Michele A Basso (MA)

Departments of Psychiatry and Biobehavioral Sciences and Neurobiology, UCLA, Los Angeles, CA 90095, USA.

Giacomo Benvenuti (G)

Departments of Psychology and Neuroscience, Center for Perceptual Systems, University of Texas, Austin, TX 78712, USA.

Martin O Bohlen (MO)

Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.

Michael J Caiola (MJ)

Yerkes National Primate Research Center, Morris K. Udall Center of Excellence for Parkinson's Disease, Department of Neurology, Emory University, GA 30329, USA.

Roberto Calcedo (R)

Gene Therapy Program, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19014, USA.

James Cavanaugh (J)

Laboratory of Sensorimotor Research, National Eye Institute, NIH, Bethesda, MD 20982, USA.

Yuzhi Chen (Y)

Departments of Psychology and Neuroscience, Center for Perceptual Systems, University of Texas, Austin, TX 78712, USA.

Spencer Chen (S)

Departments of Psychology and Neuroscience, Center for Perceptual Systems, University of Texas, Austin, TX 78712, USA.

Mykyta M Chernov (MM)

Division of Neuroscience, Oregon National Primate Resource Center, Oregon Health and Science University, Beaverton, OR 97006, USA.

Andrew M Clark (AM)

Department of Ophthalmology, Moran Eye Institute, University of Utah, Salt Lake City, UT 84132, USA.

Ji Dai (J)

CAS Key Laboratory of Brain Connectome and Manipulation, The Brain Cognition and Brain Disease Institute, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen-Hong Kong Institute of Brain Science, Shenzhen 518055, China.

Samantha R Debes (SR)

Department of Neurobiology and Anatomy, McGovern Medical School, University of Texas-Houston, Houston, TX 77030, USA.

Karl Deisseroth (K)

Neuroscience Program, Departments of Bioengineering, Psychiatry, and Behavioral Science, Wu Tsai Neurosciences Institute, Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.

Robert Desimone (R)

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Valentin Dragoi (V)

Department of Neurobiology and Anatomy, McGovern Medical School, University of Texas-Houston, Houston, TX 77030, USA.

Seth W Egger (SW)

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Mark A G Eldridge (MAG)

Laboratory of Neuropsychology, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA.

Hala G El-Nahal (HG)

Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.

Francesco Fabbrini (F)

Laboratory of Neuro- and Psychophysiology, KU Leuven, 3000 Leuven, Belgium; Leuven Brain Institute, KU Leuven, 3000 Leuven, Belgium.

Frederick Federer (F)

Department of Ophthalmology, Moran Eye Institute, University of Utah, Salt Lake City, UT 84132, USA.

Christopher R Fetsch (CR)

The Solomon H. Snyder Department of Neuroscience & Zanvyl Krieger Mind/Brain Institute, Johns Hopkins University, Baltimore, MD 21218, USA.

Michal G Fortuna (MG)

German Primate Center - Leibniz Institute for Primate Research, 37077 Göttingen, Germany.

Robert M Friedman (RM)

Division of Neuroscience, Oregon National Primate Resource Center, Oregon Health and Science University, Beaverton, OR 97006, USA.

Naotaka Fujii (N)

Laboratory for Adaptive Intelligence, RIKEN Brain Science Institute, Wako, Saitama 351-0198, Japan.

Alexander Gail (A)

German Primate Center - Leibniz Institute for Primate Research, 37077 Göttingen, Germany; Bernstein Center for Computational Neuroscience, Göttingen, Germany; Faculty for Biology and Psychology, University of Göttingen, Göttingen, Germany; Leibniz Science Campus Primate Cognition, Göttingen, Germany.

Adriana Galvan (A)

Yerkes National Primate Research Center, Morris K. Udall Center of Excellence for Parkinson's Disease, Department of Neurology, Emory University, GA 30329, USA.

Supriya Ghosh (S)

Department of Neurobiology and Grossman Institute for Neuroscience, Quantitative Biology and Human Behavior, University of Chicago, Chicago, IL 60637, USA.

Marc Alwin Gieselmann (MA)

Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle NE2 4HH, UK.

Roberto A Gulli (RA)

Zuckerman Institute, Columbia University, New York, NY 10027, USA; Center for Theoretical Neuroscience, Columbia University, New York, NY 10027, USA.

Okihide Hikosaka (O)

Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Eghbal A Hosseini (EA)

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Xing Hu (X)

Yerkes National Primate Research Center, Morris K. Udall Center of Excellence for Parkinson's Disease, Department of Neurology, Emory University, GA 30329, USA.

Janina Hüer (J)

German Primate Center - Leibniz Institute for Primate Research, 37077 Göttingen, Germany.

Ken-Ichi Inoue (KI)

Systems Neuroscience Section, Primate Research Institute, Kyoto University, Inuyama, Aichi 484-8506, Japan; PRESTO, Japan Science and Technology Agency, Kawaguchi, Saitama 332-0012, Japan.

Roger Janz (R)

Department of Neurobiology and Anatomy, McGovern Medical School, University of Texas-Houston, Houston, TX 77030, USA.

Mehrdad Jazayeri (M)

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Rundong Jiang (R)

School of Life Sciences, Peking University, Beijing 100871, China.

Niansheng Ju (N)

School of Life Sciences, Peking University, Beijing 100871, China.

Kohitij Kar (K)

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Carsten Klein (C)

Max Planck Institute for Biological Cybernetics, Tübingen, Germany.

Adam Kohn (A)

Dominik P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

Misako Komatsu (M)

Laboratory for Adaptive Intelligence, RIKEN Brain Science Institute, Wako, Saitama 351-0198, Japan.

Kazutaka Maeda (K)

Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Julio C Martinez-Trujillo (JC)

Robarts Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada; Brain and Mind Institute, University of Western Ontario, London, ON, Canada.

Masayuki Matsumoto (M)

Division of Biomedical Science, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan; Transborder Medical Research Center, University of Tsukuba, Tsukuba, Ibaraki 305-8577, Japan.

John H R Maunsell (JHR)

Department of Neurobiology and Grossman Institute for Neuroscience, Quantitative Biology and Human Behavior, University of Chicago, Chicago, IL 60637, USA.

Diego Mendoza-Halliday (D)

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Ilya E Monosov (IE)

Department of Neuroscience, Biomedical Engineering, Electrical Engineering, Neurosurgery and Pain Center, Washington University, St. Louis, MO 63110, USA.

Ross S Muers (RS)

Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle NE2 4HH, UK.

Lauri Nurminen (L)

Department of Ophthalmology, Moran Eye Institute, University of Utah, Salt Lake City, UT 84132, USA.

Michael Ortiz-Rios (M)

German Primate Center - Leibniz Institute for Primate Research, 37077 Göttingen, Germany; Leibniz Science Campus Primate Cognition, Göttingen, Germany; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle NE2 4HH, UK.

Daniel J O'Shea (DJ)

Department of Electrical Engineering, Wu Tsai Neurosciences Institute, and Bio-X Institute, and Neuroscience Graduate Program, Stanford University, Stanford, CA 94305, USA.

Stéphane Palfi (S)

Department of Neurosurgery, Assistance Publique-Hopitaux de Paris (APHP), U955 INSERM IMRB eq.15, University of Paris 12 UPEC, Faculté de Médecine, Créteil 94010, France.

Christopher I Petkov (CI)

Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle NE2 4HH, UK.

Sorin Pojoga (S)

Department of Neurobiology and Anatomy, McGovern Medical School, University of Texas-Houston, Houston, TX 77030, USA.

Rishi Rajalingham (R)

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Charu Ramakrishnan (C)

Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.

Evan D Remington (ED)

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Cambria Revsine (C)

Department of Neuroscience, University of Pennsylvania, Philadelphia, PA 19104, USA; Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20814, USA.

Anna W Roe (AW)

Division of Neuroscience, Oregon National Primate Resource Center, Oregon Health and Science University, Beaverton, OR 97006, USA; Interdisciplinary Institute of Neuroscience and Technology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310029, China; Key Laboratory of Biomedical Engineering of the Ministry of Education, Zhejiang University, Hangzhou 310029, China.

Philip N Sabes (PN)

Center for Integrative Neuroscience, University of California, San Francisco, San Francisco, CA 94158, USA.

Richard C Saunders (RC)

Laboratory of Neuropsychology, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA.

Hansjörg Scherberger (H)

German Primate Center - Leibniz Institute for Primate Research, 37077 Göttingen, Germany; Bernstein Center for Computational Neuroscience, Göttingen, Germany; Faculty for Biology and Psychology, University of Göttingen, Göttingen, Germany; Leibniz Science Campus Primate Cognition, Göttingen, Germany.

Michael C Schmid (MC)

Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle NE2 4HH, UK; Department of Neurosciences and Movement Sciences, Faculty of Science and Medicine, University of Fribourg, 1700 Fribourg, Switzerland.

Wolfram Schultz (W)

Department of Physiology, Development of Neuroscience, University of Cambridge, Cambridge CB3 0LT, UK.

Eyal Seidemann (E)

Departments of Psychology and Neuroscience, Center for Perceptual Systems, University of Texas, Austin, TX 78712, USA.

Yann-Suhan Senova (YS)

Department of Neurosurgery, Assistance Publique-Hopitaux de Paris (APHP), U955 INSERM IMRB eq.15, University of Paris 12 UPEC, Faculté de Médecine, Créteil 94010, France.

Michael N Shadlen (MN)

Department of Neuroscience, Mortimer B. Zuckerman Mind Brain Behavior Institute, The Kavli Institute for Brain Science & Howard Hughes Medical Institute, Columbia University, NY 10027, USA.

David L Sheinberg (DL)

Department of Neuroscience and Carney Institute for Brain Science, Brown University, Providence, RI 02912, USA.

Caitlin Siu (C)

Department of Ophthalmology, Moran Eye Institute, University of Utah, Salt Lake City, UT 84132, USA.

Yoland Smith (Y)

Yerkes National Primate Research Center, Morris K. Udall Center of Excellence for Parkinson's Disease, Department of Neurology, Emory University, GA 30329, USA.

Selina S Solomon (SS)

Dominik P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

Marc A Sommer (MA)

Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.

John L Spudich (JL)

Department of Biochemistry and Molecular Biology, McGovern Medical School, The University of Texas-Houston, Houston, TX 77030, USA.

William R Stauffer (WR)

Systems Neuroscience Institute, Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA 15260, USA.

Masahiko Takada (M)

Systems Neuroscience Section, Primate Research Institute, Kyoto University, Inuyama, Aichi 484-8506, Japan.

Shiming Tang (S)

School of Life Sciences, Peking University, Beijing 100871, China.

Alexander Thiele (A)

Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle NE2 4HH, UK.

Stefan Treue (S)

German Primate Center - Leibniz Institute for Primate Research, 37077 Göttingen, Germany; Bernstein Center for Computational Neuroscience, Göttingen, Germany; Faculty for Biology and Psychology, University of Göttingen, Göttingen, Germany; Leibniz Science Campus Primate Cognition, Göttingen, Germany.

Wim Vanduffel (W)

Laboratory of Neuro- and Psychophysiology, KU Leuven, 3000 Leuven, Belgium; Leuven Brain Institute, KU Leuven, 3000 Leuven, Belgium; MGH Martinos Center, Charlestown, MA 02129, USA; Harvard Medical School, Boston, MA 02144, USA.

Rufin Vogels (R)

Laboratory of Neuro- and Psychophysiology, KU Leuven, 3000 Leuven, Belgium; Leuven Brain Institute, KU Leuven, 3000 Leuven, Belgium.

Matthew P Whitmire (MP)

Departments of Psychology and Neuroscience, Center for Perceptual Systems, University of Texas, Austin, TX 78712, USA.

Thomas Wichmann (T)

Yerkes National Primate Research Center, Morris K. Udall Center of Excellence for Parkinson's Disease, Department of Neurology, Emory University, GA 30329, USA.

Robert H Wurtz (RH)

Laboratory of Sensorimotor Research, National Eye Institute, NIH, Bethesda, MD 20982, USA.

Haoran Xu (H)

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Azadeh Yazdan-Shahmorad (A)

Center for Integrative Neuroscience, University of California, San Francisco, San Francisco, CA 94158, USA; Departments of Bioengineering and Electrical and Computer Engineering, Washington National Primate Research Center, University of Washington, Seattle, WA 98105, USA.

Krishna V Shenoy (KV)

Departments of Electrical Engineering, Bioengineering, and Neurobiology, Wu Tsai Neurosciences Institute and Bio-X Institute, Neuroscience Graduate Program, and Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.

James J DiCarlo (JJ)

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Michael L Platt (ML)

Department of Neuroscience, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Psychology, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Marketing, Wharton School, University of Pennsylvania, Philadelphia, PA 19104, USA.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › An Open Resource for Non-human Primate Optogenetics.
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › An Open Resource for Non-human Primate Optogenetics.
questionsmedicales.fr › Cellules › Neurones › An Open Resource for Non-human Primate Optogenetics.
questionsmedicales.fr › Disciplines des sciences naturelles › Disciplines des sciences biologiques › Neurosciences › An Open Resource for Non-human Primate Optogenetics.
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Optogénétique › An Open Resource for Non-human Primate Optogenetics.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › An Open Resource for Non-human Primate Optogenetics.