Adipokines and Inflammation: Focus on Cardiovascular Diseases.
adipokines
cardiovascular diseases
inflammation
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
18 Oct 2020
18 Oct 2020
Historique:
received:
15
09
2020
revised:
14
10
2020
accepted:
16
10
2020
entrez:
21
10
2020
pubmed:
22
10
2020
medline:
24
2
2021
Statut:
epublish
Résumé
It is well established that adipose tissue, apart from its energy storage function, acts as an endocrine organ that produces and secretes a number of bioactive substances, including hormones commonly known as adipokines. Obesity is a major risk factor for the development of cardiovascular diseases, mainly due to a low grade of inflammation and the excessive fat accumulation produced in this state. The adipose tissue dysfunction in obesity leads to an aberrant release of adipokines, some of them with direct cardiovascular and inflammatory regulatory functions. Inflammation is a common link between obesity and cardiovascular diseases, so this review will summarise the role of the main adipokines implicated in the regulation of the inflammatory processes occurring under the scenario of cardiovascular diseases.
Identifiants
pubmed: 33081064
pii: ijms21207711
doi: 10.3390/ijms21207711
pmc: PMC7589803
pii:
doi:
Substances chimiques
Adipokines
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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