Tracking personalized functional health in older adults using geriatric assessments.

Functional health Geriatric assessments Health status indicators Mixed effects modeling Older adults Personalized functional health trajectory

Journal

BMC medical informatics and decision making
ISSN: 1472-6947
Titre abrégé: BMC Med Inform Decis Mak
Pays: England
ID NLM: 101088682

Informations de publication

Date de publication:
20 10 2020
Historique:
received: 16 09 2020
accepted: 07 10 2020
entrez: 21 10 2020
pubmed: 22 10 2020
medline: 9 1 2021
Statut: epublish

Résumé

Higher levels of functional health in older adults leads to higher quality of life and improves the ability to age-in-place. Tracking functional health objectively could help clinicians to make decisions for interventions in case of health deterioration. Even though several geriatric assessments capture several aspects of functional health, there is limited research in longitudinally tracking personalized functional health of older adults using a combination of these assessments. We used geriatric assessment data collected from 150 older adults to develop and validate a functional health prediction model based on risks associated with falls, hospitalizations, emergency visits, and death. We used mixed effects logistic regression to construct the model. The geriatric assessments included were Activities of Daily Living (ADL), Instrumental Activities of Daily Living (IADL), Mini-Mental State Examination (MMSE), Geriatric Depression Scale (GDS), and Short Form 12 (SF12). Construct validators such as fall risks associated with model predictions, and case studies with functional health trajectories were used to validate the model. The model is shown to separate samples with and without adverse health event outcomes with an area under the receiver operating characteristic curve (AUC) of > 0.85. The model could predict emergency visit or hospitalization with an AUC of 0.72 (95% CI 0.65-0.79), fall with an AUC of 0.86 (95% CI 0.83-0.89), fall with hospitalization with an AUC of 0.89 (95% CI 0.85-0.92), and mortality with an AUC of 0.93 (95% CI 0.88-0.97). Multiple comparisons of means using Turkey HSD test show that model prediction means for samples with no adverse health events versus samples with fall, hospitalization, and death were statistically significant (p < 0.001). Case studies for individual residents using predicted functional health trajectories show that changes in model predictions over time correspond to critical health changes in older adults. The personalized functional health tracking may provide clinicians with a longitudinal view of overall functional health in older adults to help address the early detection of deterioration trends and decide appropriate interventions. It can also help older adults and family members take proactive steps to improve functional health.

Sections du résumé

BACKGROUND
Higher levels of functional health in older adults leads to higher quality of life and improves the ability to age-in-place. Tracking functional health objectively could help clinicians to make decisions for interventions in case of health deterioration. Even though several geriatric assessments capture several aspects of functional health, there is limited research in longitudinally tracking personalized functional health of older adults using a combination of these assessments.
METHODS
We used geriatric assessment data collected from 150 older adults to develop and validate a functional health prediction model based on risks associated with falls, hospitalizations, emergency visits, and death. We used mixed effects logistic regression to construct the model. The geriatric assessments included were Activities of Daily Living (ADL), Instrumental Activities of Daily Living (IADL), Mini-Mental State Examination (MMSE), Geriatric Depression Scale (GDS), and Short Form 12 (SF12). Construct validators such as fall risks associated with model predictions, and case studies with functional health trajectories were used to validate the model.
RESULTS
The model is shown to separate samples with and without adverse health event outcomes with an area under the receiver operating characteristic curve (AUC) of > 0.85. The model could predict emergency visit or hospitalization with an AUC of 0.72 (95% CI 0.65-0.79), fall with an AUC of 0.86 (95% CI 0.83-0.89), fall with hospitalization with an AUC of 0.89 (95% CI 0.85-0.92), and mortality with an AUC of 0.93 (95% CI 0.88-0.97). Multiple comparisons of means using Turkey HSD test show that model prediction means for samples with no adverse health events versus samples with fall, hospitalization, and death were statistically significant (p < 0.001). Case studies for individual residents using predicted functional health trajectories show that changes in model predictions over time correspond to critical health changes in older adults.
CONCLUSIONS
The personalized functional health tracking may provide clinicians with a longitudinal view of overall functional health in older adults to help address the early detection of deterioration trends and decide appropriate interventions. It can also help older adults and family members take proactive steps to improve functional health.

Identifiants

pubmed: 33081769
doi: 10.1186/s12911-020-01283-y
pii: 10.1186/s12911-020-01283-y
pmc: PMC7576843
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

270

Subventions

Organisme : NIDDK NIH HHS
ID : P30 DK092950
Pays : United States
Organisme : NINR NIH HHS
ID : R01 NR016423
Pays : United States

Références

J Am Geriatr Soc. 2000 Sep;48(9):1132-5
pubmed: 10983915
Gerontologist. 1969 Autumn;9(3):179-86
pubmed: 5349366
J Clin Epidemiol. 2011 Jul;64(7):749-59
pubmed: 21208778
J Am Geriatr Soc. 2008 Jan;56(1):68-75
pubmed: 18031487
J Am Geriatr Soc. 1992 Dec;40(12):1227-30
pubmed: 1447439
J Gen Intern Med. 2009 Oct;24(10):1115-22
pubmed: 19649678
J Psychiatr Res. 1982-1983;17(1):37-49
pubmed: 7183759
Nurs Outlook. 2005 Jan-Feb;53(1):40-5
pubmed: 15761399
J Public Health Med. 1997 Jun;19(2):179-86
pubmed: 9243433
J Psychiatr Res. 1975 Nov;12(3):189-98
pubmed: 1202204
Med Care. 1996 Mar;34(3):220-33
pubmed: 8628042
J Gerontol A Biol Sci Med Sci. 2017 Aug 1;72(8):1123-1129
pubmed: 28329788
Pediatrics. 1993 Mar;91(3):617-23
pubmed: 8441569
J Am Geriatr Soc. 2007 Dec;55(12):1955-60
pubmed: 17944891
Br J Anaesth. 2007 Jun;98(6):704-6
pubmed: 17519260
J Am Geriatr Soc. 1985 Apr;33(4):228-35
pubmed: 3989183
BMJ Open. 2017 Dec 26;7(12):e019503
pubmed: 29282274
CMAJ. 2005 Aug 30;173(5):489-95
pubmed: 16129869
Arch Gerontol Geriatr. 2010 May-Jun;50(3):306-10
pubmed: 19520442
Lancet. 2008 Mar 1;371(9614):725-35
pubmed: 18313501
J Alzheimers Dis. 2018;62(3):993-1012
pubmed: 29562543
Acad Emerg Med. 2004 Feb;11(2):162-8
pubmed: 14759959
J Gerontol A Biol Sci Med Sci. 2001 Mar;56(3):M146-56
pubmed: 11253156
Arch Intern Med. 2001 Nov 26;161(21):2602-7
pubmed: 11718592
J Clin Epidemiol. 1998 Nov;51(11):1171-8
pubmed: 9817135
JAMA. 2006 Feb 15;295(7):801-8
pubmed: 16478903
Am J Obstet Gynecol. 2006 Mar;194(3):888-94
pubmed: 16522430

Auteurs

Anup K Mishra (AK)

Department of Electrical Engineering and Computer Science, University of Missouri, Columbia, MO, 65211, USA. akmm94@mail.missouri.edu.

Marjorie Skubic (M)

Department of Electrical Engineering and Computer Science, University of Missouri, Columbia, MO, 65211, USA.

Mihail Popescu (M)

Department of Health Management and Informatics, University of Missouri, Columbia, MO, 65211, USA.

Kari Lane (K)

Sinclair School of Nursing, University of Missouri, Columbia, MO, 65211, USA.

Marilyn Rantz (M)

Sinclair School of Nursing, University of Missouri, Columbia, MO, 65211, USA.

Laurel A Despins (LA)

Sinclair School of Nursing, University of Missouri, Columbia, MO, 65211, USA.

Carmen Abbott (C)

School of Health Professions, Physical Therapy, University of Missouri, Columbia, MO, 65211, USA.

James Keller (J)

Department of Electrical Engineering and Computer Science, University of Missouri, Columbia, MO, 65211, USA.

Erin L Robinson (EL)

School of Social Work, University of Missouri, Columbia, MO, 65211, USA.

Steve Miller (S)

Sinclair School of Nursing, University of Missouri, Columbia, MO, 65211, USA.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH