Modified self-obtained pooled sampling to screen for
Adult
Ambulatory Care Facilities
Chlamydia Infections
/ diagnosis
Chlamydia trachomatis
/ isolation & purification
Gonorrhea
/ diagnosis
Homosexuality, Male
Humans
Japan
/ epidemiology
Male
Mass Screening
/ methods
Middle Aged
Neisseria gonorrhoeae
/ isolation & purification
Nucleic Acid Amplification Techniques
/ methods
Pharynx
/ microbiology
Prospective Studies
Rectum
/ microbiology
Sensitivity and Specificity
Sexual and Gender Minorities
Specimen Handling
/ methods
Urine
/ microbiology
Chlamydia trachomatis
Neisseria gonorrhoeae
screening
sexual health
Journal
Sexually transmitted infections
ISSN: 1472-3263
Titre abrégé: Sex Transm Infect
Pays: England
ID NLM: 9805554
Informations de publication
Date de publication:
08 2021
08 2021
Historique:
received:
23
06
2020
revised:
14
08
2020
accepted:
27
09
2020
pubmed:
22
10
2020
medline:
15
12
2021
entrez:
21
10
2020
Statut:
ppublish
Résumé
To assess whether pooled sample testing with nucleic acid amplification tests was a potential alternative to three single-site sample testing to screen for We prospectively compared pooled sample testing with single-site sample testing in asymptomatic MSM. Self-obtained paired rectal samples, one gargle sample and one first-void urine sample were collected from participants to generate two sets of samples: one for pooled sample testing and the other for single-site testing. We used modified pooled sampling, which is defined as the use of gargle samples, instead of swabs, for the pooled sample to test for pharyngeal infection. This study included 513 MSM. The positive rates of The modified pooled sampling had a comparably high consistency with single-site sample testing. The results strongly suggest that the gargle sample is suitable as a part of pooled sample for STI screening of
Identifiants
pubmed: 33082236
pii: sextrans-2020-054666
doi: 10.1136/sextrans-2020-054666
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
324-328Informations de copyright
© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: SO has received research grants/materials from Gilead Sciences, MSD KK, CSL Behring and ViiV Healthcare, Co., and has received honorarium for lectures from MSD KK, Gilead Sciences, ViiV Healthcare and Janssen Pharmaceutical, KK.