Study of antibacterial and antifungal efficacy of platelet-rich fibrin and platelet-rich fibrin matrix.
Antimicrobial property
oral Candida albicans
platelet rich fibrin
platelet rich fibrin matrix
root canal flora
Journal
Journal of conservative dentistry : JCD
ISSN: 0972-0707
Titre abrégé: J Conserv Dent
Pays: India
ID NLM: 101147009
Informations de publication
Date de publication:
Historique:
received:
25
10
2019
revised:
09
03
2020
accepted:
04
06
2020
entrez:
21
10
2020
pubmed:
22
10
2020
medline:
22
10
2020
Statut:
ppublish
Résumé
Platelet concentrates are extensively utilized in the medical and dental field to promote tissue regeneration. The profusion of endogenous growth factors in platelets α-granules transmit their use for enhanced wound healing. However, little attention has been given to study their antimicrobial potential. This study was conducted to assess the antibacterial and antifungal property of platelet-rich fibrin (PRF) and PRF matrix (PRFM). Blood samples were obtained from 16 participants, PRF and PRFM were processed as per the protocol prescribed by Choukroun PRF showed an effective antibacterial property, however, did not perform well against C. albicans strains. PRFM did not show any antibacterial or antifungal properties. The antibacterial efficacy of PRF may prove beneficial when used in the revascularization procedure of immature necrotic teeth.
Sections du résumé
BACKGROUND
BACKGROUND
Platelet concentrates are extensively utilized in the medical and dental field to promote tissue regeneration. The profusion of endogenous growth factors in platelets α-granules transmit their use for enhanced wound healing. However, little attention has been given to study their antimicrobial potential. This study was conducted to assess the antibacterial and antifungal property of platelet-rich fibrin (PRF) and PRF matrix (PRFM).
MATERIALS AND METHODOLOGY
METHODS
Blood samples were obtained from 16 participants, PRF and PRFM were processed as per the protocol prescribed by Choukroun
RESULTS
RESULTS
PRF showed an effective antibacterial property, however, did not perform well against C. albicans strains. PRFM did not show any antibacterial or antifungal properties.
CONCLUSIONS
CONCLUSIONS
The antibacterial efficacy of PRF may prove beneficial when used in the revascularization procedure of immature necrotic teeth.
Identifiants
pubmed: 33082654
doi: 10.4103/JCD.JCD_100_19
pii: JCD-22-415
pmc: PMC7537747
doi:
Types de publication
Journal Article
Langues
eng
Pagination
415-419Informations de copyright
Copyright: © 2020 Journal of Conservative Dentistry.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
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