Single probe diffuse reflectance spectroscopy to assess the effect of sarcopoterium spinosum treatment on the cerebral tissue properties of ApoE knockout mouse.

Sarcopoterium spinosum biochemical and histological analysis cerebral hemodynamics diffuse reflectance spectroscopy tissue parameters

Journal

Journal of biophotonics
ISSN: 1864-0648
Titre abrégé: J Biophotonics
Pays: Germany
ID NLM: 101318567

Informations de publication

Date de publication:
02 2021
Historique:
received: 28 07 2020
revised: 11 10 2020
accepted: 13 10 2020
pubmed: 22 10 2020
medline: 13 7 2021
entrez: 21 10 2020
Statut: ppublish

Résumé

In this work, diffuse near-infrared light reflectance spectroscopy based on a single optical probe, contains central single collection fiber surrounded by a circular array of illumination fibers, was used to quantify cerebral tissue properties in ApoE knockout mice following Sarcopoterium spinosum treatment. Sarcopoterium spinosum, also known as Thorny burnet, is a Mediterranean plant widely used as a traditional therapy for the treatment of a variety of pathologies, primarily type 2 diabetes mellitus (T2D). While it's efficacy in the treatment of T2D, and of other components of metabolic syndrome, have already been validated by us, the aim of this study was to investigate the effects of Sarcopoterium spinosum extract (SSE) on dyslipidemia and vascular functions. We utilized ApoE deficient mice (ApoE

Identifiants

pubmed: 33084182
doi: 10.1002/jbio.202000307
doi:

Substances chimiques

Plant Extracts 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e202000307

Informations de copyright

© 2020 Wiley-VCH GmbH.

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Auteurs

David Shemesh (D)

Department of Electrical and Electronics Engineering, Ariel University, Ariel, Israel.

Konstantin Rozenberg (K)

Departments of Molecular Biology and Nutritional Studies, Ariel University, Ariel, Israel.

Tovit Rosenzweig (T)

Departments of Molecular Biology and Nutritional Studies, Ariel University, Ariel, Israel.

David Abookasis (D)

Department of Electrical and Electronics Engineering, Ariel University, Ariel, Israel.

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