Optogenetic Control of the BMP Signaling Pathway.

Bone Morphogenetic Proteins / genetics Cell Line DNA-Binding Proteins / genetics HEK293 Cells Humans Optogenetics / methods Phosphorylation / genetics Signal Transduction / genetics Trans-Activators / genetics Transforming Growth Factor beta / genetics
BMP signaling cell signaling chondrocytes light-oxygen-voltage (LOV)-sensing domain optogenetics

Journal

ACS synthetic biology
ISSN: 2161-5063
Titre abrégé: ACS Synth Biol
Pays: United States
ID NLM: 101575075

Informations de publication

Date de publication:
20 11 2020
Historique:
pubmed: 22 10 2020
medline: 25 8 2021
entrez: 21 10 2020
Statut: ppublish

Résumé

Bone morphogenetic proteins (BMPs) are members of the transforming growth factor β (TGFβ) superfamily and have crucial roles during development; including mesodermal patterning and specification of renal, hepatic, and skeletal tissues.

Identifiants

DOI: 10.1021/acssynbio.0c00315 PMID: 33084303 PMC: PMC7927147
pubmed: 33084303
doi: 10.1021/acssynbio.0c00315
pmc: PMC7927147
doi:

Substances chimiques

Bone Morphogenetic Proteins 0
DNA-Binding Proteins 0
Trans-Activators 0
Transforming Growth Factor beta 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3067-3078

Subventions

Organisme : Medical Research Council
ID : MR/L004992/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/L011840/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/S002553/1
Pays : United Kingdom

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Auteurs

Paul A Humphreys (PA)

Division of Cell Matrix & Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PL, U.K.
Division of Neuroscience & Experimental Psychology, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PL, U.K.
ORCID: 0000-0002-1833-4864

Steven Woods (S)

Division of Cell Matrix & Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PL, U.K.

Christopher A Smith (CA)

Division of Cell Matrix & Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PL, U.K.

Nicola Bates (N)

Division of Cell Matrix & Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PL, U.K.

Stuart A Cain (SA)

Division of Cell Matrix & Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PL, U.K.

Robert Lucas (R)

Division of Neuroscience & Experimental Psychology, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PL, U.K.

Susan J Kimber (SJ)

Division of Cell Matrix & Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PL, U.K.

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Protéines de la superfamille du TGF bêta › Protéines morphogénétiques osseuses › Optogenetic Control of the BMP Signaling Pathway.
questionsmedicales.fr › Cellules › Cellules cultivées › Lignée cellulaire › Optogenetic Control of the BMP Signaling Pathway.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de liaison à l'ADN › Optogenetic Control of the BMP Signaling Pathway.
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules HEK293 › Optogenetic Control of the BMP Signaling Pathway.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Optogenetic Control of the BMP Signaling Pathway.
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Optogénétique › Optogenetic Control of the BMP Signaling Pathway.
questionsmedicales.fr › Métabolisme › Phosphorylation › Optogenetic Control of the BMP Signaling Pathway.
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Optogenetic Control of the BMP Signaling Pathway.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines virales › Protéines virales régulatrices ou accessoires › Transactivateurs › Optogenetic Control of the BMP Signaling Pathway.
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Protéines de la superfamille du TGF bêta › Facteur de croissance transformant bêta › Optogenetic Control of the BMP Signaling Pathway.