Evaluation of overall and disease-free survival in patients with free flaps for oral cancer resection.


Journal

Microsurgery
ISSN: 1098-2752
Titre abrégé: Microsurgery
Pays: United States
ID NLM: 8309230

Informations de publication

Date de publication:
Nov 2020
Historique:
received: 07 05 2020
revised: 27 08 2020
accepted: 18 09 2020
pubmed: 22 10 2020
medline: 13 7 2021
entrez: 21 10 2020
Statut: ppublish

Résumé

Sarcopenia is characterized by depletion of skeletal muscle mass (SMM) and can cause increased postoperative complication in free flap procedure. One of the most important considerations while deciding the indication of the procedure is patients' survival. This study aimed to verify the relationship between low SMM and survival in patients who undergo oral cancer resection using free flap. SMM was evaluated using the skeletal muscle index (SMI cm A total of 25 patients (22.5%) were diagnosed with low SMM. The mean SMI was 42.2 cm Low SMM is a significant negative prognostic factor for overall and disease-free survival in oral cancer patients undergoing free flap. Future prospective studies are warranted to identify effective preoperative exercise and nutrition programs to improve low skeletal muscle and survival rate in patients undergoing free flap procedures.

Identifiants

pubmed: 33085115
doi: 10.1002/micr.30668
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

859-867

Informations de copyright

© 2020 Wiley Periodicals LLC.

Références

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Auteurs

Takaya Makiguchi (T)

Department of Oral and Maxillofacial Surgery, and Plastic Surgery, Gunma University Graduate School of Medicine, Gunma, Japan.

Takahiro Yamaguchi (T)

Department of Oral and Maxillofacial Surgery, and Plastic Surgery, Gunma University Graduate School of Medicine, Gunma, Japan.

Hideharu Nakamura (H)

Department of Oral and Maxillofacial Surgery, and Plastic Surgery, Gunma University Graduate School of Medicine, Gunma, Japan.

Yukie Yamatsu (Y)

Department of Oral and Maxillofacial Surgery, and Plastic Surgery, Gunma University Graduate School of Medicine, Gunma, Japan.

Yuki Hirai (Y)

Department of Oral and Maxillofacial Surgery, and Plastic Surgery, Gunma University Graduate School of Medicine, Gunma, Japan.

Koki Shoda (K)

Department of Oral and Maxillofacial Surgery, and Plastic Surgery, Gunma University Graduate School of Medicine, Gunma, Japan.

Sasagu Kurozumi (S)

Department of General Surgical Science, Gunma University Graduate School of Medicine, Gunma, Japan.

Soichiro Ibaragi (S)

Department of Oral and Maxillofacial Surgery, and Plastic Surgery, Gunma University Graduate School of Medicine, Gunma, Japan.

Norifumi Harimoto (N)

Department of General Surgical Science, Gunma University Graduate School of Medicine, Gunma, Japan.

Sei-Ichiro Motegi (SI)

Department of Dermatology, Gunma University Graduate School of Medicine, Gunma, Japan.

Ken Shirabe (K)

Department of General Surgical Science, Gunma University Graduate School of Medicine, Gunma, Japan.

Satoshi Yokoo (S)

Department of Oral and Maxillofacial Surgery, and Plastic Surgery, Gunma University Graduate School of Medicine, Gunma, Japan.

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