A flexible method for optimising sharing of healthcare resources and demand in the context of the COVID-19 pandemic.
Algorithms
Betacoronavirus
COVID-19
Coronavirus Infections
/ epidemiology
Critical Care
Health Resources
/ supply & distribution
Hospital Bed Capacity
Humans
Intensive Care Units
/ supply & distribution
Models, Theoretical
Pandemics
Patient Transfer
Pneumonia, Viral
/ epidemiology
SARS-CoV-2
Spain
/ epidemiology
United Kingdom
/ epidemiology
Ventilators, Mechanical
/ supply & distribution
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2020
2020
Historique:
received:
13
07
2020
accepted:
22
09
2020
entrez:
21
10
2020
pubmed:
22
10
2020
medline:
3
11
2020
Statut:
epublish
Résumé
As the number of cases of COVID-19 continues to grow, local health services are at risk of being overwhelmed with patients requiring intensive care. We develop and implement an algorithm to provide optimal re-routing strategies to either transfer patients requiring Intensive Care Units (ICU) or ventilators, constrained by feasibility of transfer. We validate our approach with realistic data from the United Kingdom and Spain. In the UK, we consider the National Health Service at the level of trusts and define a 4-regular geometric graph which indicates the four nearest neighbours of any given trust. In Spain we coarse-grain the healthcare system at the level of autonomous communities, and extract similar contact networks. Through random search optimisation we identify the best load sharing strategy, where the cost function to minimise is based on the total number of ICU units above capacity. Our framework is general and flexible allowing for additional criteria, alternative cost functions, and can be extended to other resources beyond ICU units or ventilators. Assuming a uniform ICU demand, we show that it is possible to enable access to ICU for up to 1000 additional cases in the UK in a single step of the algorithm. Under a more realistic and heterogeneous demand, our method is able to balance about 600 beds per step in the Spanish system only using local sharing, and over 1300 using countrywide sharing, potentially saving a large percentage of these lives that would otherwise not have access to ICU.
Identifiants
pubmed: 33085729
doi: 10.1371/journal.pone.0241027
pii: PONE-D-20-21713
pmc: PMC7577502
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0241027Subventions
Organisme : Medical Research Council
ID : MC_PC_19067
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/V038613/1
Pays : United Kingdom
Commentaires et corrections
Type : ErratumIn
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
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JAMA. 2020 Apr 28;323(16):1545-1546
pubmed: 32167538