The structural basis for Z α


Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
10 2020
Historique:
received: 09 05 2020
accepted: 08 09 2020
entrez: 22 10 2020
pubmed: 23 10 2020
medline: 23 10 2020
Statut: epublish

Résumé

The serpinopathies are among a diverse set of conformational diseases that involve the aberrant self-association of proteins into ordered aggregates. α

Identifiants

pubmed: 33087346
pii: 6/43/eabc1370
doi: 10.1126/sciadv.abc1370
pmc: PMC7577719
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/N024842/1
Pays : United Kingdom

Informations de copyright

Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).

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Auteurs

Sarah V Faull (SV)

UCL Respiratory, University College London, 5 University Street, London WC1E 6JF, UK.

Emma L K Elliston (ELK)

UCL Respiratory, University College London, 5 University Street, London WC1E 6JF, UK.
Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BN, UK.

Bibek Gooptu (B)

Leicester Institute of Structural and Chemical Biology, University of Leicester, Henry Wellcome Building, Lancaster Road, Leicester LE1 7HB, UK.
National Institute for Health Research (NIHR) Leicester BRC-Respiratory, Leicester, UK.
Institute of Structural and Molecular Biology, Birkbeck College, Malet Street, University of London, London WC1E 7HX, UK.

Alistair M Jagger (AM)

UCL Respiratory, University College London, 5 University Street, London WC1E 6JF, UK.
Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BN, UK.

Ibrahim Aldobiyan (I)

UCL Respiratory, University College London, 5 University Street, London WC1E 6JF, UK.
Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BN, UK.

Adam Redzej (A)

Institute of Structural and Molecular Biology, Birkbeck College, Malet Street, University of London, London WC1E 7HX, UK.

Magd Badaoui (M)

UCL Respiratory, University College London, 5 University Street, London WC1E 6JF, UK.

Nina Heyer-Chauhan (N)

UCL Respiratory, University College London, 5 University Street, London WC1E 6JF, UK.
Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BN, UK.

S Tamir Rashid (ST)

Centre for Stem Cells and Regenerative Medicine and Institute for Liver Studies, King's College London, London WC2R 2LS, UK.

Gary M Reynolds (GM)

Centre for Liver Research and NIHR Birmingham Liver Biomedical Research Unit, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.

David H Adams (DH)

Centre for Liver Research and NIHR Birmingham Liver Biomedical Research Unit, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.

Elena Miranda (E)

Department of Biology and Biotechnologies "Charles Darwin" and Pasteur Institute-Cenci Bolognetti Foundation, Sapienza University of Rome, Rome, Italy.

Elena V Orlova (EV)

Institute of Structural and Molecular Biology, Birkbeck College, Malet Street, University of London, London WC1E 7HX, UK.

James A Irving (JA)

UCL Respiratory, University College London, 5 University Street, London WC1E 6JF, UK. j.irving@ucl.ac.uk d.lomas@ucl.ac.uk.
Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BN, UK.

David A Lomas (DA)

UCL Respiratory, University College London, 5 University Street, London WC1E 6JF, UK. j.irving@ucl.ac.uk d.lomas@ucl.ac.uk.
Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BN, UK.

Classifications MeSH