Characteristics and Outcomes of Latinx Patients With COVID-19 in Comparison With Other Ethnic and Racial Groups.

COVID-19 SARS-CoV-2 disparities ethnicity hospitalizations race

Journal

Open forum infectious diseases
ISSN: 2328-8957
Titre abrégé: Open Forum Infect Dis
Pays: United States
ID NLM: 101637045

Informations de publication

Date de publication:
Oct 2020
Historique:
received: 03 08 2020
accepted: 26 08 2020
entrez: 22 10 2020
pubmed: 23 10 2020
medline: 23 10 2020
Statut: epublish

Résumé

There is a limited understanding of the impact of coronavirus disease 2019 (COVID-19) on the Latinx population. We hypothesized that Latinx patients would be more likely to be hospitalized and admitted to the intensive care unit (ICU) than White patients. We analyzed all patients with COVID-19 in 12 Massachusetts hospitals between February 1 and April 14, 2020. We examined the association between race, ethnicity, age, reported comorbidities, and hospitalization and ICU admission using multivariable regression. Of 5190 COVID-19 patients, 29% were hospitalized; 33% required the ICU, and 4.3% died. Forty-six percent of patients were White, 25% Latinx, 14% African American, and 3% Asian American. Ethnicity and race were significantly associated with hospitalization. More Latinx and African American patients in the younger age groups were hospitalized than whites. Latinxs and African Americans disproportionally required the ICU, with 39% of hospitalized Latinx patients requiring the ICU compared with 33% of African Americans, 24% of Asian Americans, and 30% of Whites ( Latinx and African American patients with COVID-19 have higher rates of hospitalization and ICU admission than White patients. The etiologies of such disparities are likely multifactorial and cannot be explained only by reported comorbidities.

Sections du résumé

BACKGROUND BACKGROUND
There is a limited understanding of the impact of coronavirus disease 2019 (COVID-19) on the Latinx population. We hypothesized that Latinx patients would be more likely to be hospitalized and admitted to the intensive care unit (ICU) than White patients.
METHODS METHODS
We analyzed all patients with COVID-19 in 12 Massachusetts hospitals between February 1 and April 14, 2020. We examined the association between race, ethnicity, age, reported comorbidities, and hospitalization and ICU admission using multivariable regression.
RESULTS RESULTS
Of 5190 COVID-19 patients, 29% were hospitalized; 33% required the ICU, and 4.3% died. Forty-six percent of patients were White, 25% Latinx, 14% African American, and 3% Asian American. Ethnicity and race were significantly associated with hospitalization. More Latinx and African American patients in the younger age groups were hospitalized than whites. Latinxs and African Americans disproportionally required the ICU, with 39% of hospitalized Latinx patients requiring the ICU compared with 33% of African Americans, 24% of Asian Americans, and 30% of Whites (
CONCLUSIONS CONCLUSIONS
Latinx and African American patients with COVID-19 have higher rates of hospitalization and ICU admission than White patients. The etiologies of such disparities are likely multifactorial and cannot be explained only by reported comorbidities.

Identifiants

pubmed: 33088846
doi: 10.1093/ofid/ofaa401
pii: ofaa401
pmc: PMC7499713
doi:

Types de publication

Journal Article

Langues

eng

Pagination

ofaa401

Subventions

Organisme : NIAID NIH HHS
ID : U01 AI136816
Pays : United States

Informations de copyright

© The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

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Auteurs

Saef Izzy (S)

Department of Neurology, Neurocritical Care, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Center for Immunology & Inflammatory Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Harvard Medical School, Boston, Massachusetts, USA.

Zabreen Tahir (Z)

Department of Neurology, Neurocritical Care, Brigham and Women's Hospital, Boston, Massachusetts, USA.

David J Cote (DJ)

Harvard Medical School, Boston, Massachusetts, USA.

Ali Al Jarrah (A)

Department of Neurology, Neurocritical Care, Brigham and Women's Hospital, Boston, Massachusetts, USA.

Matthew Blake Roberts (MB)

Department of Medicine, Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Harvard Medical School, Boston, Massachusetts, USA.

Sarah Turbett (S)

Harvard Medical School, Boston, Massachusetts, USA.
Department of Medicine, Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA.

Aran Kadar (A)

Department of Medicine, Division of Pulmonary Critical Care, Newton Wellesley Hospital, Newton, Massachusetts.

Stelios M Smirnakis (SM)

Department of Neurology, Neurocritical Care, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Harvard Medical School, Boston, Massachusetts, USA.

Steven K Feske (SK)

Department of Neurology, Neurocritical Care, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Harvard Medical School, Boston, Massachusetts, USA.

Ross Zafonte (R)

Harvard Medical School, Boston, Massachusetts, USA.
Department of Physical Medicine and Rehabilitation Massachusetts General Hospital, Boston, Massachusetts, USA.
Spaulding Rehabilitation Hospital, Charlestown, Massachusetts, USA.

Jay A Fishman (JA)

Harvard Medical School, Boston, Massachusetts, USA.
Department of Medicine, Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.

Joseph El Khoury (J)

Center for Immunology & Inflammatory Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Harvard Medical School, Boston, Massachusetts, USA.
Department of Medicine, Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.

Classifications MeSH