The Impact of Preoperative Inflammatory Markers on the Prognosis of Patients Undergoing Surgical Resection of Pulmonary Oligometastases.
C-reactive protein
neutrophils
pulmonary oligometastases
surgery
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
21 Oct 2020
21 Oct 2020
Historique:
received:
17
09
2020
revised:
16
10
2020
accepted:
19
10
2020
entrez:
24
10
2020
pubmed:
25
10
2020
medline:
25
10
2020
Statut:
epublish
Résumé
The aim of this study was to assess the prognostic value of preoperative neutrophil-to-lymphocyte ratio (NLR) and C-reactive protein (CRP) levels in patients undergoing resection of pulmonary oligometastases. A retrospective analysis on 141 patients undergoing a first pulmonary metastasectomy in a single center was carried out. Two distinct analysis were performed subdividing patients according to their NLR ratio and CRP level. The main outcomes were survival and time to recurrence. At completion of follow-up 74 patients were still alive (52.5%). Subdividing patients according to their NLR yielded a significant difference in five-year progression-free survival (PFS, NLR < 4:32% vs. NLR ≥ 4:18%,
Identifiants
pubmed: 33096884
pii: jcm9103378
doi: 10.3390/jcm9103378
pmc: PMC7590166
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
J Natl Cancer Inst. 2014 May 29;106(6):dju124
pubmed: 24875653
Aging Dis. 2020 Feb 1;11(1):129-140
pubmed: 32010487
Cell Mol Life Sci. 2014 Nov;71(21):4179-94
pubmed: 25070012
J Thorac Cardiovasc Surg. 1997 Jan;113(1):37-49
pubmed: 9011700
Chest. 1995 Jun;107(6 Suppl):322S-331S
pubmed: 7781414
Oncotarget. 2017 May 30;8(22):36566-36577
pubmed: 28402263
Interact Cardiovasc Thorac Surg. 2015 Nov;21(5):616-23
pubmed: 26242317
Proc Natl Acad Sci U S A. 2012 Aug 7;109(32):13076-81
pubmed: 22826226
Eur J Cardiothorac Surg. 2019 May 1;55(5):948-955
pubmed: 30508167
Surg Oncol. 2006 Dec;15(4):217-22
pubmed: 17320378
Ann Thorac Surg. 1997 Mar;63(3):777-84
pubmed: 9066401
Br J Cancer. 2007 Nov 5;97(9):1266-70
pubmed: 17923866
J Surg Oncol. 2016 Dec;114(7):895-899
pubmed: 27696432
Epidemiology. 2007 Nov;18(6):805-35
pubmed: 18049195
Br J Cancer. 2015 Jul 14;113(2):204-11
pubmed: 26125452
Biol Chem. 2015 Nov;396(11):1181-97
pubmed: 26040008
Int J Clin Exp Med. 2015 Aug 15;8(8):13571-7
pubmed: 26550296
Clin Immunol. 2005 Nov;117(2):104-11
pubmed: 16214080
J Clin Oncol. 1995 Jan;13(1):8-10
pubmed: 7799047
PLoS One. 2016 Apr 22;11(4):e0150586
pubmed: 27104349
Int J Colorectal Dis. 2010 Dec;25(12):1427-33
pubmed: 20821217
Ann Surg Oncol. 2019 Mar;26(3):869-875
pubmed: 30607764
Inflammation. 2013 Dec;36(6):1485-93
pubmed: 23872721
Nature. 2002 Dec 19-26;420(6917):860-7
pubmed: 12490959
J Thorac Cardiovasc Surg. 2007 Apr;133(4):967-72
pubmed: 17382635
Cancer Lett. 2010 Feb 28;288(2):162-9
pubmed: 19646811
Cancer Res. 2006 Jan 1;66(1):259-66
pubmed: 16397239
Front Immunol. 2019 Apr 30;10:943
pubmed: 31114584
Br J Cancer. 2011 Apr 12;104(8):1288-95
pubmed: 21448173
Clin Genitourin Cancer. 2013 Jun;11(2):141-8
pubmed: 23083797
Crit Rev Clin Lab Sci. 2011 Jul-Aug;48(4):155-70
pubmed: 22035340
Cancer Treat Rev. 2013 Aug;39(5):534-40
pubmed: 22995477