Generation of the induced pluripotent stem cell line UHOMi002-A from peripheral blood mononuclear cells of a healthy male donor.
Journal
Stem cell research
ISSN: 1876-7753
Titre abrégé: Stem Cell Res
Pays: England
ID NLM: 101316957
Informations de publication
Date de publication:
12 2020
12 2020
Historique:
received:
18
09
2020
revised:
30
09
2020
accepted:
05
10
2020
pubmed:
26
10
2020
medline:
22
6
2021
entrez:
25
10
2020
Statut:
ppublish
Résumé
Human pluripotent stem cells (hiPSC) are highly valuable tools to model lung development and chronic bronchial diseases. We generated a hiPSC line from a highly characterized 40-year-old healthy male nonsmoking donor. Peripheral blood mononuclear cells (PBMCs) were reprogrammed using integration-free Sendai Virus. The cell line had normal karyotype, expressed pluripotency hallmarks, and differentiated into the three primary germ layers. The reported UHOMi002-A iPSC line may be used as a control to model lung development, study human chronic bronchial diseases and drug testing.
Identifiants
pubmed: 33099111
pii: S1873-5061(20)30338-X
doi: 10.1016/j.scr.2020.102037
pii:
doi:
Substances chimiques
Transcription Factors
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
102037Informations de copyright
Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.