Genome sequencing identifies a rare case of moderate Zellweger spectrum disorder caused by a

ES, exome sequencing GS, genome sequencing Genetic testing Genome sequencing IRD, infantile Refsum disease MAF, minor allele frequency NALD, neonatal adrenoleukodystrophy PBD, peroxisome biogenesis disorder PEX3 PMP, peroxisomal membrane protein Peroxisome biogenesis disorder RCDP, rhizomelic chondrodysplasia punctata VLCFA, very-long chain fatty acids X-ALD, X-linked adrenoleukodystrophy ZS, Zellweger syndrome ZSD, Zellweger spectrum disorder Zellweger spectrum disorder gnomAD, Genome Aggregate Database

Journal

Molecular genetics and metabolism reports
ISSN: 2214-4269
Titre abrégé: Mol Genet Metab Rep
Pays: United States
ID NLM: 101624422

Informations de publication

Date de publication:
Dec 2020
Historique:
received: 06 07 2020
revised: 09 10 2020
accepted: 10 10 2020
entrez: 26 10 2020
pubmed: 27 10 2020
medline: 27 10 2020
Statut: epublish

Résumé

Defects in

Identifiants

pubmed: 33101983
doi: 10.1016/j.ymgmr.2020.100664
pii: S2214-4269(20)30110-5
pmc: PMC7578253
doi:

Types de publication

Case Reports

Langues

eng

Pagination

100664

Informations de copyright

© 2020 The Authors.

Déclaration de conflit d'intérêts

The authors declare no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Références

J Hum Genet. 2019 Feb;64(2):145-152
pubmed: 30237433
Am J Hum Genet. 2000 Oct;67(4):967-75
pubmed: 10958759
J Pediatr. 1995 Oct;127(4):596-9
pubmed: 7562283
Am J Hum Genet. 2012 Sep 7;91(3):408-21
pubmed: 22939633
Brain Dev. 2013 Oct;35(9):842-8
pubmed: 23245813
NPJ Genom Med. 2016 Jan 13;1:
pubmed: 28567303
PLoS One. 2011;6(8):e22984
pubmed: 21826223
Bioinformatics. 2016 Apr 15;32(8):1220-2
pubmed: 26647377
Am J Hum Genet. 2019 Oct 3;105(4):719-733
pubmed: 31564432
Hum Mutat. 2004 Jun;23(6):552-8
pubmed: 15146459
Genome Res. 2011 Jun;21(6):974-84
pubmed: 21324876
JAMA Netw Open. 2020 Sep 1;3(9):e2018109
pubmed: 32960281
Genet Med. 2018 Apr;20(4):435-443
pubmed: 28771251
Mol Genet Metab. 2017 Aug;121(4):325-328
pubmed: 28673549
Hum Mol Genet. 2000 Aug 12;9(13):1995-9
pubmed: 10942428
JIMD Rep. 2017;34:71-75
pubmed: 27557811
Biochim Biophys Acta. 2006 Dec;1763(12):1733-48
pubmed: 17055079
J Inherit Metab Dis. 2009 Dec;32 Suppl 1:S345-8
pubmed: 20033294
Nature. 2020 May;581(7809):434-443
pubmed: 32461654
Am J Hum Genet. 2000 Oct;67(4):976-81
pubmed: 10968777

Auteurs

Whiwon Lee (W)

Centre for Genetic Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.

Gregory Costain (G)

Centre for Genetic Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, Toronto, Ontario, Canada.

Susan Blaser (S)

Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Ontario, Canada.

Susan Walker (S)

The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, Ontario, Canada.

Christian R Marshall (CR)

Centre for Genetic Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
Genome Diagnostics, Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.

Hernan Gonorazky (H)

Division of Neurology, The Hospital for Sick Children, Toronto, Ontario, Canada.

Michal Inbar-Feigenberg (M)

Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, Toronto, Ontario, Canada.

Classifications MeSH