Three cases of pulmonary tumor thrombotic microangiopathy (PTTM): Challenge in antemortem diagnosis using lung perfusion blood volume images by dual-energy computed tomography.
Dual-energy computed tomography (CT)
Lung perfused blood volume (PBV) images
Pulmonary hypertension
Pulmonary tumor thrombotic microangiopathy (PTTM)
Journal
European journal of radiology open
ISSN: 2352-0477
Titre abrégé: Eur J Radiol Open
Pays: England
ID NLM: 101650225
Informations de publication
Date de publication:
2020
2020
Historique:
received:
08
12
2019
revised:
14
12
2019
accepted:
05
01
2020
entrez:
26
10
2020
pubmed:
27
10
2020
medline:
27
10
2020
Statut:
epublish
Résumé
Pulmonary tumor thrombotic microangiopathy (PTTM) is a specific type of tumor embolism in the small and medium pulmonary arteries, leading to rapid progressive pulmonary hypertension. Antemortem diagnosis of PTTM is extremely difficult. We encountered three patients who were histopathologically or clinically diagnosed with PTTM. In all cases, lung perfused blood volume (PBV) images on dual-energy computed tomography (CT) demonstrated multiple subpleural wedge-shaped defects with no evidence of pulmonary embolism on CT pulmonary angiography. The lung PBV images demonstrated small pulmonary arterial obstruction reflecting the pathology of PTTM. Therefore, lung PBV imaging would be useful for antemortem diagnosis of PTTM.
Identifiants
pubmed: 33102634
doi: 10.1016/j.ejro.2020.01.001
pii: S2352-0477(20)30001-0
pmc: PMC7569404
doi:
Types de publication
Case Reports
Langues
eng
Pagination
100212Informations de copyright
© 2020 The Authors.
Déclaration de conflit d'intérêts
None.
Références
Pulm Circ. 2019 Apr-Jun;9(2):2045894019851000
pubmed: 31032740
Ann Diagn Pathol. 2000 Jun;4(3):154-7
pubmed: 10919385
Eur J Nucl Med Mol Imaging. 2003 Feb;30(2):288-95
pubmed: 12552348
AJR Am J Roentgenol. 2012 Nov;199(5 Suppl):S3-8
pubmed: 23097165
Intern Med. 2019 May 1;58(9):1311-1314
pubmed: 30626821
Case Rep Oncol. 2017 Jul 11;10(2):620-626
pubmed: 28868021
Cancer. 1990 Aug 1;66(3):587-92
pubmed: 2163747
J Med Case Rep. 2017 Dec 23;11(1):356
pubmed: 29273073
Intern Med. 2013;52(12):1317-23
pubmed: 23774540
Curr Opin Pulm Med. 2016 Sep;22(5):421-8
pubmed: 27387102
Eur J Radiol. 2008 Dec;68(3):369-74
pubmed: 18775618
BMJ Case Rep. 2017 Jun 28;2017:
pubmed: 28659364
Clin Nucl Med. 2009 Mar;34(3):175-7
pubmed: 19352285
Intern Med. 2017;56(1):67-71
pubmed: 28050002