Preclinical validation of therapeutic targets predicted by tensor factorization on heterogeneous graphs.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
26 10 2020
26 10 2020
Historique:
received:
22
01
2020
accepted:
30
09
2020
entrez:
27
10
2020
pubmed:
28
10
2020
medline:
13
3
2021
Statut:
epublish
Résumé
Incorrect drug target identification is a major obstacle in drug discovery. Only 15% of drugs advance from Phase II to approval, with ineffective targets accounting for over 50% of these failures
Identifiants
pubmed: 33106501
doi: 10.1038/s41598-020-74922-z
pii: 10.1038/s41598-020-74922-z
pmc: PMC7589557
doi:
Types de publication
Journal Article
Validation Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
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