The Role of Zyxin in Carcinogenesis.

Animals Carcinogenesis / metabolism Humans Neoplasms / metabolism Zyxin / chemistry
LIM domain proteins Zyxin cancer review

Journal

Anticancer research
ISSN: 1791-7530
Titre abrégé: Anticancer Res
Pays: Greece
ID NLM: 8102988

Informations de publication

Date de publication:
Nov 2020
Historique:
received: 23 09 2020
revised: 02 10 2020
accepted: 05 10 2020
entrez: 28 10 2020
pubmed: 29 10 2020
medline: 5 11 2020
Statut: ppublish

Résumé

Zyxin (ZYX) is a LIM domain protein whose presence has been detected in the cytoplasm and nucleus. ZYX can translocate between these two compartments and therefore, can take part in the regulation of various cellular processes. VASP and α-actinin are examples of proteins that interact with ZYX. As ZYX is present in focal adhesions (FAs), an immense part of research is focused on the role of this protein in the organisation and function of the cytoskeleton. Other studies aim to explain the impact of zyxin on other intracellular processes. Zyxin has been shown to take part in apoptosis, as well as in wound healing. Additionally, zyxin contribution to cancer development is gaining growing interest. This paper aims to systematise the knowledge on zyxin and its role in carcinogenesis.

Identifiants

DOI: 10.21873/anticanres.14618 PMID: 33109535
pubmed: 33109535
pii: 40/11/5981
doi: 10.21873/anticanres.14618
doi:

Substances chimiques

Zyxin 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

5981-5988

Informations de copyright

Copyright© 2020, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Auteurs

Aleksandra Partynska (A)

Department of Histology and Embryology, Department of Human Morphology and Embryology, Faculty of Medicine, Wroclaw Medical University, Wroclaw, Poland ola.partynska@onet.pl.

Agnieszka Gomulkiewicz (A)

Department of Histology and Embryology, Department of Human Morphology and Embryology, Faculty of Medicine, Wroclaw Medical University, Wroclaw, Poland.

Piotr Dziegiel (P)

Department of Histology and Embryology, Department of Human Morphology and Embryology, Faculty of Medicine, Wroclaw Medical University, Wroclaw, Poland.
Human Biology Unit, Faculty of Physiotherapy, University School of Physical Education in Wroclaw, Wroclaw, Poland.

Marzenna Podhorska-Okolow (M)

Department of Ultrastructural Research, Faculty of Medicine, Wroclaw Medical University, Wroclaw, Poland.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › The Role of Zyxin in Carcinogenesis.
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Processus néoplasiques › Carcinogenèse › The Role of Zyxin in Carcinogenesis.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The Role of Zyxin in Carcinogenesis.
questionsmedicales.fr › Tumeurs › The Role of Zyxin in Carcinogenesis.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Phosphoprotéines › Zyxine › The Role of Zyxin in Carcinogenesis.