Prognostic significance of the sum of the diameters of single foci in multifocal papillary thyroid cancer: the concept of new-old tumor burden.
bilaterality
multifocality
papillary thyroid cancer
sum of diameters of single foci
tumor burden
Journal
Therapeutic advances in endocrinology and metabolism
ISSN: 2042-0188
Titre abrégé: Ther Adv Endocrinol Metab
Pays: United States
ID NLM: 101532143
Informations de publication
Date de publication:
2020
2020
Historique:
received:
10
06
2020
accepted:
11
09
2020
entrez:
28
10
2020
pubmed:
29
10
2020
medline:
29
10
2020
Statut:
epublish
Résumé
The prognostic value of multifocality (Mu) in papillary thyroid cancer (PTC) remains controversial. The present study aimed to investigate this issue and test the possible prognostic significance of the sum of the diameters of single foci (SDSF), the total number of foci (TNF), and primary tumor size (PTS) in multifocal PTC. We retrospectively analyzed a single-center consecutive series of 370 PTCs. For multifocal cases we analyzed bilaterality occurrence, SDSF, TNF, and PTS. Mu was observed in 41.1% PTCs, and bilaterality in 30%. Mu was associated with an advanced T-category. In bilateral multifocal PTC, the PTS was larger, and microPTC was less frequent, while T-categories were higher. Mu and bilaterality Mu and bilaterality
Identifiants
pubmed: 33110488
doi: 10.1177/2042018820964326
pii: 10.1177_2042018820964326
pmc: PMC7557686
doi:
Types de publication
Journal Article
Langues
eng
Pagination
2042018820964326Informations de copyright
© The Author(s), 2020.
Déclaration de conflit d'intérêts
Conflict of interest statement: The authors declare that there is no conflict of interest.
Références
Ann Surg Oncol. 2015 Jan;22(1):125-31
pubmed: 25092159
JAMA Otolaryngol Head Neck Surg. 2014 Apr;140(4):317-22
pubmed: 24557566
Ann Surg. 2005 Nov;242(5):708-15
pubmed: 16244545
World J Surg. 2013 Feb;37(2):376-84
pubmed: 23135422
PLoS One. 2017 Nov 10;12(11):e0188031
pubmed: 29125877
J Endocrinol Invest. 2020 May;43(5):601-613
pubmed: 31749082
Eur J Endocrinol. 2006 Jun;154(6):787-803
pubmed: 16728537
Curr Treat Options Oncol. 2017 Jul;18(7):40
pubmed: 28555375
Ann Surg. 2018 Jan;267(1):132-141
pubmed: 27763897
World J Surg. 2016 Sep;40(9):2139-43
pubmed: 27412628
Medicine (Baltimore). 2018 Feb;97(5):e9619
pubmed: 29384841
Oral Oncol. 2019 Jul;94:106-110
pubmed: 31178204
CA Cancer J Clin. 2014 Jan-Feb;64(1):9-29
pubmed: 24399786
Oral Oncol. 2017 Feb;65:1-7
pubmed: 28109462
J Clin Endocrinol Metab. 2006 Jan;91(1):313-9
pubmed: 16263822
Oncology (Williston Park). 2018 Sep 18;32(9):e90-e96
pubmed: 30248170
Sci Rep. 2017 May 12;7(1):1846
pubmed: 28500312
J Clin Endocrinol Metab. 2017 Sep 1;102(9):3241-3250
pubmed: 28582521
BMC Cancer. 2014 Dec 04;14:914
pubmed: 25471041
Crit Rev Oncol Hematol. 2014 Apr;90(1):17-23
pubmed: 24290380
Cancer Manag Res. 2018 Sep 03;10:3169-3175
pubmed: 30214309
Int J Clin Exp Pathol. 2014 Aug 15;7(9):5393-403
pubmed: 25337182
Cancer. 1997 Jun 15;79(12):2414-23
pubmed: 9191532
J Endocrinol Invest. 2014 Jun;37(6):593-9
pubmed: 24789536
Asian J Surg. 2019 Jan;42(1):297-302
pubmed: 30585170
Oral Oncol. 2017 Aug;71:81-86
pubmed: 28688696
Oral Oncol. 2018 Dec;87:158-164
pubmed: 30527232
Lancet. 2003 Feb 8;361(9356):501-11
pubmed: 12583960
J Otolaryngol Head Neck Surg. 2010 Jun;39(3):284-7
pubmed: 20470673
Vestn Ross Akad Med Nauk. 2014;(11-12):67-71
pubmed: 25971129
Thyroid. 2019 Apr;29(4):513-522
pubmed: 30799769
Thyroid. 2016 Jan;26(1):1-133
pubmed: 26462967
Int J Surg. 2018 Feb;50:121-125
pubmed: 29337178
Eur J Endocrinol. 2019 Jul 1;181(1):1-11
pubmed: 31042674
Tumour Biol. 2016 Jul;37(7):8783-9
pubmed: 26743781