Pain in long-term survivors of childhood cancer: A systematic review of the current state of knowledge and a call to action from the Children's Oncology Group.


Journal

Cancer
ISSN: 1097-0142
Titre abrégé: Cancer
Pays: United States
ID NLM: 0374236

Informations de publication

Date de publication:
01 01 2021
Historique:
received: 08 09 2020
revised: 06 10 2020
accepted: 06 10 2020
pubmed: 29 10 2020
medline: 8 9 2021
entrez: 28 10 2020
Statut: ppublish

Résumé

Survivors of childhood cancer may be at risk of experiencing pain, and a systematic review would advance our understanding of pain in this population. The objective of this study was to describe: 1) the prevalence of pain in survivors of childhood cancer, 2) methods of pain measurement, 3) associations between pain and biopsychosocial factors, and 4) recommendations for future research. Data sources for the study were articles published from January 1990 to August 2019 identified in the PubMed, PsycINFO, EMBASE, and Web of Science data bases. Eligible studies included: 1) original research, 2) quantitative assessments of pain, 3) articles published in English, 4) cancers diagnosed between birth and age 21 years, 5) survivors at 5 years from diagnosis and/or at 2 years after therapy completion, and 6) a sample size >20. Seventy-three articles were included in the final review. Risk of bias was considered using the Cochrane risk of bias tool. The quality of evidence was evaluated according to Grading of Recommendations Assessment Development and Evaluation (GRADE) criteria. Common measures of pain were items created by the authors for the purpose of the study (45.2%) or health-related quality-of-life/health status questionnaires (42.5%). Pain was present in from 4.3% to 75% of survivors across studies. Three studies investigated chronic pain according the definition in the International Classification of Diseases. The findings indicated that survivors of childhood cancer are at higher risk of experiencing pain compared with controls. Fatigue was consistently associated with pain, females reported more pain than males, and other factors related to pain will require stronger evidence. Theoretically grounded, multidimensional measurements of pain are absent from the literature.

Identifiants

pubmed: 33112416
doi: 10.1002/cncr.33289
pmc: PMC7875461
mid: NIHMS1664448
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

35-44

Subventions

Organisme : NCI NIH HHS
ID : U10 CA180886
Pays : United States
Organisme : NCI NIH HHS
ID : U10 CA180899
Pays : United States
Organisme : NCI NIH HHS
ID : UG1 CA189955
Pays : United States

Informations de copyright

© 2020 American Cancer Society.

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Auteurs

Fiona S M Schulte (FSM)

Department of Oncology, Division of Psychosocial Oncology, University of Calgary, Calgary, Alberta, Canada.
Hematology, Oncology, and Transplant Program, Alberta Children's Hospital, Calgary, Alberta, Canada.

Michaela Patton (M)

Department of Psychology, University of Calgary, Calgary, Alberta, Canada.

Nicole M Alberts (NM)

Department of Psychology, Concordia University, Montreal, Quebec, Canada.

Alicia Kunin-Batson (A)

Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

Barbara A Olson-Bullis (BA)

HealthPartners Institute, Minneapolis, Minnesota.

Caitlin Forbes (C)

Department of Oncology, Division of Psychosocial Oncology, University of Calgary, Calgary, Alberta, Canada.

K Brooke Russell (KB)

Department of Psychology, University of Calgary, Calgary, Alberta, Canada.

Alexandra Neville (A)

Department of Psychology, University of Calgary, Calgary, Alberta, Canada.

Lauren C Heathcote (LC)

Department of Anesthesiology, Perioperative, and Pain Medicine, Stanford University Medical School, Stanford, California.

Cynthia W Karlson (CW)

Department of Pediatrics, University of Mississippi Medical Center, Jackson, Mississippi.

Nicole M Racine (NM)

Department of Psychology, University of Calgary, Calgary, Alberta, Canada.

Courtney Charnock (C)

Department of Oncology, Division of Psychosocial Oncology, University of Calgary, Calgary, Alberta, Canada.

Matthew C Hocking (MC)

Center for Childhood Cancer Research and Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania.

Pia Banerjee (P)

Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, Tennessee.

Perri R Tutelman (PR)

Departments of Psychology and Neuroscience, Dalhousie University, Halifax, Nova Scotia, Canada.

Melanie Noel (M)

Department of Psychology, University of Calgary, Calgary, Alberta, Canada.

Kevin R Krull (KR)

Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, Tennessee.

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