Treosulfan-Based Conditioning Regimen for Second Allograft in Patients with Myelofibrosis.
myelofibrosis
second allogeneic transplant
stem cell transplantation
treosulfan
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
23 Oct 2020
23 Oct 2020
Historique:
received:
31
08
2020
revised:
15
10
2020
accepted:
21
10
2020
entrez:
29
10
2020
pubmed:
30
10
2020
medline:
30
10
2020
Statut:
epublish
Résumé
Relapse after allogeneic hematopoietic stem cell transplantation (AHSCT) in myelofibrosis (MF) patients remains as a significant issue despite advances in transplantation procedures and significant prolongation in survival. Second AHSCT is a potential treatment option but associated with high treatment-related mortality and novel less toxic conditioning regimens are needed. In 33 MF patients with relapse after AHSCT and failure to donor lymphocyte infusion (DLI) we investigated treosulfan (36-42 g/m
Identifiants
pubmed: 33114179
pii: cancers12113098
doi: 10.3390/cancers12113098
pmc: PMC7690833
pii:
doi:
Types de publication
Journal Article
Langues
eng
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