Meta-analysis on short-term exposure to ambient ultrafine particles and respiratory morbidity.
Journal
European respiratory review : an official journal of the European Respiratory Society
ISSN: 1600-0617
Titre abrégé: Eur Respir Rev
Pays: England
ID NLM: 9111391
Informations de publication
Date de publication:
31 Dec 2020
31 Dec 2020
Historique:
received:
23
04
2020
accepted:
22
05
2020
entrez:
29
10
2020
pubmed:
30
10
2020
medline:
25
11
2021
Statut:
epublish
Résumé
There is growing interest in the health effects following exposure to ambient particles with a diameter <100 nm defined as ultrafine particles (UFPs), although studies so far have reported inconsistent results. We have undertaken a systematic review and meta-analysis for respiratory hospital admissions and emergency room visits following short-term exposure to UFPs. We searched PubMed and the Web of Science for studies published up to March 2019 to update previous reviews. We applied fixed- and random-effects models, assessed heterogeneity between cities and explored possible effect modifiers. We identified nine publications, reporting effects from 15 cities, 11 of which were European. There was great variability in exposure assessment, outcome measures and the exposure lags considered. Our meta-analyses did not support UFP effects on respiratory morbidity across all ages. We found consistent statistically significant associations following lag 2 exposure during the warm period and in cities with mean daily UFP concentrations <6000 particles·cm Our study indicates UFP effects on respiratory health among children, and during the warm season across all ages at longer lags. The limited evidence and the large heterogeneity of previous reports call for future exposure assessment harmonisation and expanded research.
Identifiants
pubmed: 33115789
pii: 29/158/200116
doi: 10.1183/16000617.0116-2020
pmc: PMC9488642
pii:
doi:
Substances chimiques
Particulate Matter
0
Types de publication
Journal Article
Meta-Analysis
Review
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright ©ERS 2020.
Déclaration de conflit d'intérêts
Conflict of interest: E. Samoli has nothing to disclose. Conflict of interest: S. Rodopoulou has nothing to disclose. Conflict of interest: A. Schneider reports grants from German Environment Agency, German Foundation of Heart Research, German Federal Ministry of Education and Research and US Environmental Protection Agency, outside the submitted work. Conflict of interest: L. Morawska has nothing to disclose. Conflict of interest: M. Stafoggia has nothing to disclose. Conflict of interest: M. Renzi has nothing to disclose. Conflict of interest: S. Breitner reports grants from German Environment Agency and US Environmental Protection Agency, outside the submitted work. Conflict of interest: T. Lanki has nothing to disclose. Conflict of interest: R. Pickford reports grants from Interreg Central Europe, outside the submitted work. Conflict of interest: T. Schikowski has nothing to disclose. Conflict of interest: O. Enembe has nothing to disclose. Conflict of interest: S. Zhang has nothing to disclose. Conflict of interest: Q. Zhao has nothing to disclose. Conflict of interest: A. Peters has nothing to disclose.
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