Exuberant fibroblast activity compromises lung function via ADAMTS4.
ADAMTS4 Protein
/ antagonists & inhibitors
Animals
Birds
/ virology
Extracellular Matrix
/ enzymology
Fibroblasts
/ enzymology
Gene Expression Profiling
Humans
Influenza A virus
/ pathogenicity
Influenza in Birds
/ virology
Influenza, Human
/ pathology
Interferons
/ immunology
Leukocyte Common Antigens
/ metabolism
Lung
/ enzymology
Mice
Respiratory Distress Syndrome
/ enzymology
Seasons
Single-Cell Analysis
Stromal Cells
/ metabolism
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
11 2020
11 2020
Historique:
received:
16
07
2019
accepted:
30
07
2020
pubmed:
30
10
2020
medline:
18
2
2021
entrez:
29
10
2020
Statut:
ppublish
Résumé
Severe respiratory infections can result in acute respiratory distress syndrome (ARDS)
Identifiants
pubmed: 33116313
doi: 10.1038/s41586-020-2877-5
pii: 10.1038/s41586-020-2877-5
pmc: PMC7883627
mid: NIHMS1665566
doi:
Substances chimiques
Interferons
9008-11-1
Leukocyte Common Antigens
EC 3.1.3.48
ADAMTS4 Protein
EC 3.4.24.82
ADAMTS4 protein, human
EC 3.4.24.82
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
466-471Subventions
Organisme : NIAID NIH HHS
ID : T32 AI106700
Pays : United States
Organisme : NIAID NIH HHS
ID : HHSN272201400006C
Pays : United States
Organisme : NICHD NIH HHS
ID : R21 HD095228
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI084011
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI128805
Pays : United States
Organisme : NIAID NIH HHS
ID : HHSN272201400007C
Pays : United States
Organisme : NIH HHS
ID : U42 OD011158
Pays : United States
Investigateurs
Michele Kong
(M)
Ronald C Sanders
(RC)
Katherine Irby
(K)
Katri Typpo
(K)
Barry Markovitz
(B)
Natalie Cvijanovich
(N)
Heidi Flori
(H)
Adam Schwarz
(A)
Nick Anas
(N)
Peter Mourani
(P)
Angela Czaja
(A)
Gwenn McLaughlin
(G)
Matthew Paden
(M)
Keiko Tarquinio
(K)
Bria M Coates
(BM)
Neethi Pinto
(N)
Juliane Bubeck Wardenburg
(JB)
Adrienne G Randolph
(AG)
Anna A Agan
(AA)
Tanya Novak
(T)
Margaret M Newhams
(MM)
Stephen C Kurachek
(SC)
Mary E Hartman
(ME)
Allan Doctor
(A)
Edward J Truemper
(EJ)
Sidharth Mahapatra
(S)
Kate G Ackerman
(KG)
L Eugene Daugherty
(LE)
Mark W Hall
(MW)
Neal Thomas
(N)
Scott L Weiss
(SL)
Julie Fitzgerald
(J)
Renee Higgerson
(R)
Laura L Loftis
(LL)
Rainer G Gedeit
(RG)
Marc-André Dugas
(MA)
Commentaires et corrections
Type : CommentIn
Type : ErratumIn
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