A miner with No left lung: Extensive pulmonary destruction in delayed effective Multi-Drug-Resistant Tuberculosis treatment.

Complication Democratic republic of Congo Mycobacterium tuberculosis Thoracic surgery

Journal

Respiratory medicine case reports
ISSN: 2213-0071
Titre abrégé: Respir Med Case Rep
Pays: England
ID NLM: 101604463

Informations de publication

Date de publication:
2020
Historique:
received: 24 07 2020
revised: 21 09 2020
accepted: 21 09 2020
entrez: 29 10 2020
pubmed: 30 10 2020
medline: 30 10 2020
Statut: epublish

Résumé

We report a case of extensive pulmonary destruction due to delayed effective pulmonary tuberculosis (TB) treatment in an adult artisanal miner in eastern Democratic Republic of Congo. Xpert MTB/RIF was positive after his second rifampicin-susceptible TB treatment. Chest X-rays were suggestive of large cavity, fibrosis of remaining lung and air-fluid levels at the base of the destroyed lung. The patient passed away after delayed effective TB regimens. Clinicians should be aware that urgent surgical intervention is often required to prevent lethal acute respiratory failure and shock notwithstanding effective chemotherapy in such condition. Effort is needed to timely diagnose multidrug resistance TB and to implement thoracic surgery for TB in high burden countries.

Identifiants

pubmed: 33117645
doi: 10.1016/j.rmcr.2020.101234
pii: S2213-0071(20)30448-2
pmc: PMC7582097
doi:

Types de publication

Case Reports

Langues

eng

Pagination

101234

Informations de copyright

© 2020 The Author(s).

Déclaration de conflit d'intérêts

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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Auteurs

Patrick D M C Katoto (PDMC)

Department of Internal Medicine, Division of Respiratory Medicine & Prof. Lurhuma Biomedical Research Laboratory, Mycobacterium Unit, The Expertise Center on Mining Governance (CEGEMI), Catholic University of Bukavu, Bukavu, Democratic Republic of the Congo.
Department of Global Health, Centre for Infectious Diseases, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

Patrick Musole (P)

Department of Internal Medicine, Division of Respiratory Medicine & Prof. Lurhuma Biomedical Research Laboratory, Mycobacterium Unit, The Expertise Center on Mining Governance (CEGEMI), Catholic University of Bukavu, Bukavu, Democratic Republic of the Congo.

Ghislain Maheshe (G)

Department of Medical Imagery, Provincial General Hospital of Bukavu, Catholic University of Bukavu, Bukavu, Democratic Republic of the Congo.

Bertrand Bamuleke (B)

Department of Internal Medicine, Division of Respiratory Medicine & Prof. Lurhuma Biomedical Research Laboratory, Mycobacterium Unit, The Expertise Center on Mining Governance (CEGEMI), Catholic University of Bukavu, Bukavu, Democratic Republic of the Congo.

Aime Murhula (A)

Department of Internal Medicine, Division of Respiratory Medicine & Prof. Lurhuma Biomedical Research Laboratory, Mycobacterium Unit, The Expertise Center on Mining Governance (CEGEMI), Catholic University of Bukavu, Bukavu, Democratic Republic of the Congo.

Patrick Balungwe (P)

Department of Otorhinolaryngology, Provincial General Hospital of Bukavu, Catholic University of Bukavu, Bukavu, Democratic Republic of the Congo.

Liliane N Byamungu (LN)

Department of Paediatric, Provincial General Hospital of Bukavu, Catholic University of Bukavu, Bukavu, Democratic Republic of the Congo.
Department of Paediatric, University of KwaZulu Natal, Durban, South Africa.

Classifications MeSH