Effect of an educational intervention delivered by pharmacists on adherence to treatment, disease control and lung function in patients with asthma.
Administration, Inhalation
Adult
Aged
Anti-Asthmatic Agents
/ administration & dosage
Asthma
/ drug therapy
Delivery of Health Care
Female
Humans
Italy
Lung
/ physiopathology
Male
Middle Aged
Nebulizers and Vaporizers
Patient Compliance
/ psychology
Patient Education as Topic
/ methods
Pharmacists
Prospective Studies
Adherence
Asthma
Inhalers
Pharmacists
Therapy
Journal
Respiratory medicine
ISSN: 1532-3064
Titre abrégé: Respir Med
Pays: England
ID NLM: 8908438
Informations de publication
Date de publication:
Historique:
received:
24
08
2020
revised:
03
10
2020
accepted:
19
10
2020
pubmed:
30
10
2020
medline:
22
6
2021
entrez:
29
10
2020
Statut:
ppublish
Résumé
Lack of therapeutic adherence is a relevant problem in clinical practice and it can be assessed via validated tools such as the Test of Adherence to Inhalers (TAI). Education on the correct use of inhaler devices has been associated with improvement in adherence. Many studies highlighted the pivotal role of pharmacists in promoting therapeutic adherence in the management of respiratory diseases. To evaluate the effectiveness on adherence and clinical parameters of an educational intervention administered by clinical pharmacists (CPs) to patients with asthma on long-term inhalation therapy. A prospective comparative study involving 34 community pharmacies in Italy (23 intervention, 11 control). Enrolled subjects were evaluated for adherence to inhalation therapy by TAI, asthma control by "Asthma Control Test" (ACT), and lung function at baseline and after 2 months. The educational intervention at baseline was based on TAI results and administered by specifically trained pharmacists. A total of 242 consecutive subjects (167 intervention, 75 control) were enrolled. There was a significant improvement in TAI score, ACT and lung function parameters (p-value<0.001) in the intervention group between baseline and the follow-up visit. Patients with baseline ACT≥20 maintained disease control more frequently in the intervention group compared to the control arm (95% vs 79.5%, p = 0.004). Conclusions through administration of TAI-driven educational interventions addressing both technical and psychological issues, trained CPs can help improve adherence to treatment and asthma control.
Sections du résumé
BACKGROUND
Lack of therapeutic adherence is a relevant problem in clinical practice and it can be assessed via validated tools such as the Test of Adherence to Inhalers (TAI). Education on the correct use of inhaler devices has been associated with improvement in adherence. Many studies highlighted the pivotal role of pharmacists in promoting therapeutic adherence in the management of respiratory diseases.
OBJECTIVE
To evaluate the effectiveness on adherence and clinical parameters of an educational intervention administered by clinical pharmacists (CPs) to patients with asthma on long-term inhalation therapy.
METHODS
A prospective comparative study involving 34 community pharmacies in Italy (23 intervention, 11 control). Enrolled subjects were evaluated for adherence to inhalation therapy by TAI, asthma control by "Asthma Control Test" (ACT), and lung function at baseline and after 2 months. The educational intervention at baseline was based on TAI results and administered by specifically trained pharmacists.
RESULTS
A total of 242 consecutive subjects (167 intervention, 75 control) were enrolled. There was a significant improvement in TAI score, ACT and lung function parameters (p-value<0.001) in the intervention group between baseline and the follow-up visit. Patients with baseline ACT≥20 maintained disease control more frequently in the intervention group compared to the control arm (95% vs 79.5%, p = 0.004). Conclusions through administration of TAI-driven educational interventions addressing both technical and psychological issues, trained CPs can help improve adherence to treatment and asthma control.
Identifiants
pubmed: 33120195
pii: S0954-6111(20)30339-5
doi: 10.1016/j.rmed.2020.106199
pii:
doi:
Substances chimiques
Anti-Asthmatic Agents
0
Types de publication
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
106199Investigateurs
Carlotta Comar
(C)
Katia Vaiarelli
(K)
Giuliana Gioiella
(G)
Carlo Aprile
(C)
Angelo Basile
(A)
Anna Battisti
(A)
Camilla Cavalli
(C)
Mario Cirino
(M)
Mirka Dalla Bella
(MD)
Rita Demontis
(R)
Gaetano Di Donato
(G)
Rita Di Gangi
(R)
Antonio Esposito
(A)
Gyada Falanga
(G)
Patrizia Ghetti
(P)
Giuseppe Fimiani
(G)
Alessia Florio
(A)
Enrico Floris
(E)
Alessandro Fontanesi
(A)
Antonino Giuffrida
(A)
Carmelo Guccione
(C)
Laura Lancia
(L)
Anna Maria Lanzoni
(AM)
Azzurra Leo
(A)
Chiara Leone
(C)
Paolo Levantino
(P)
Matteo Marchionni
(M)
Maria Miccichè
(M)
Francesco Moneghini
(F)
Pia Policicchio
(P)
Antonio Rauseo
(A)
Flora Romano
(F)
Maria Josè Sequenza
(MJ)
Stefania Stabile
(S)
Matilde Zacchia
(M)
Stefano Iellousheg Zanetti
(SI)
Informations de copyright
Copyright © 2020 Elsevier Ltd. All rights reserved.