Association of
Adolescent
Adult
Case-Control Studies
Female
Genetic Predisposition to Disease
Humans
Interleukin-6
/ genetics
Male
Middle Aged
Multiple Sclerosis
/ complications
Optic Neuritis
/ complications
Polymorphism, Single Nucleotide
Tissue Inhibitor of Metalloproteinase-3
/ genetics
Vascular Endothelial Growth Factor A
/ genetics
Young Adult
IL-6
TIMP-3
VEGFA
Optic neuritis
multiple sclerosis
Journal
Ophthalmic genetics
ISSN: 1744-5094
Titre abrégé: Ophthalmic Genet
Pays: England
ID NLM: 9436057
Informations de publication
Date de publication:
02 2021
02 2021
Historique:
pubmed:
31
10
2020
medline:
1
9
2021
entrez:
30
10
2020
Statut:
ppublish
Résumé
The etiology of the inflammatory ON is multifactorial. Much attention is paid to the inflammatory and immune processes that are likely to contribute to the demyelination and MS development. Patients with ON, ON with MS, and a random sample of healthy population were enrolled. The genotyping of T/C and C/C genotypes of rs1413711 is associated with the ON development.
Sections du résumé
BACKGROUND
The etiology of the inflammatory ON is multifactorial. Much attention is paid to the inflammatory and immune processes that are likely to contribute to the demyelination and MS development.
MATERIALS AND METHODS
Patients with ON, ON with MS, and a random sample of healthy population were enrolled. The genotyping of
RESULTS
T/C and C/C genotypes of
CONCLUSION: VEGFA
rs1413711 is associated with the ON development.
Identifiants
pubmed: 33121296
doi: 10.1080/13816810.2020.1839916
doi:
Substances chimiques
IL6 protein, human
0
Interleukin-6
0
TIMP3 protein, human
0
Tissue Inhibitor of Metalloproteinase-3
0
VEGFA protein, human
0
Vascular Endothelial Growth Factor A
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM