Clinical and Radiologic Findings of Acute Necrotizing Encephalopathy in Young Adults.
Journal
AJNR. American journal of neuroradiology
ISSN: 1936-959X
Titre abrégé: AJNR Am J Neuroradiol
Pays: United States
ID NLM: 8003708
Informations de publication
Date de publication:
12 2020
12 2020
Historique:
received:
24
05
2020
accepted:
15
07
2020
pubmed:
31
10
2020
medline:
9
3
2021
entrez:
30
10
2020
Statut:
ppublish
Résumé
Acute necrotizing encephalopathy after an acute febrile illness, although initially described exclusively in the pediatric age group, has been recently shown to have an adult onset as well. In this study, we describe 10 patients (16 years of age or older) with acute necrotizing encephalopathy. In our study, bilateral thalamic involvement with the trilaminar pattern of diffusion restriction on MR imaging was the predominant finding seen in all of the patients reviewed. Ancillary findings of cerebral white matter, brain stem, and cerebellum involvement with sparing of the basal ganglia were also noted. A poorer outcome was observed in patients with a higher degree of thalamic involvement. The cause of an underlying infection was identified in 4 patients (dengue in 3 and influenza in 1). Overall, a sizeable portion of young adults with acute necrotizing encephalopathy have shown a poorer outcome, with dengue being an important underlying trigger in an endemic region.
Identifiants
pubmed: 33122207
pii: ajnr.A6803
doi: 10.3174/ajnr.A6803
pmc: PMC7963253
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2250-2254Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2020 by American Journal of Neuroradiology.
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