Cystatin C and uncontrolled hypertension.
Journal
Anatolian journal of cardiology
ISSN: 2149-2271
Titre abrégé: Anatol J Cardiol
Pays: Turkey
ID NLM: 101652981
Informations de publication
Date de publication:
11 2020
11 2020
Historique:
entrez:
30
10
2020
pubmed:
31
10
2020
medline:
7
8
2021
Statut:
ppublish
Résumé
Increased serum level of cystatin C, a sensitive biomarker for renal function, seems to predict adverse cardiovascular events. We investigated the predictive value of serum cystatin C for controlling hypertension in an observational study. We screened 1037 adults residing in both rural and urban communities. They were grouped based on their diagnosis and control of hypertension. Serum cystatin C levels in patients with uncontrolled hypertension were higher than those in patients with controlled hypertension (0.98±0.23 mg/L vs. 0.89±0.19 mg/L, p=0.001). However, serum creatinine levels were similar between these groups (0.72±0.20 mg/dL vs. 0.70±0.18 mg/dL, p=0.89). Serum cystatin C levels increased the probability of uncontrolled hypertension independent from confounding factors (odds ratio, 1.48; 95% confidence interval, 1.09-5.64; p=0.03). Subtle kidney dysfunction may be detected using serum cystatin C concentrations among patients with poor blood pressure control and normal serum creatinine levels.
Identifiants
pubmed: 33122483
doi: 10.14744/AnatolJCardiol.2020.78974
pmc: PMC7724385
doi:
Substances chimiques
Biomarkers
0
Cystatin C
0
Types de publication
Evaluation Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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