Onion Bulb Extract Downregulates EGFR/ERK1/2/AKT Signaling Pathway and Synergizes With Steroids to Inhibit Allergic Inflammation.
asthma
onion (Allium cepa Hysam)
signalling
steroids
synergisctic effects
Journal
Frontiers in pharmacology
ISSN: 1663-9812
Titre abrégé: Front Pharmacol
Pays: Switzerland
ID NLM: 101548923
Informations de publication
Date de publication:
2020
2020
Historique:
received:
14
04
2020
accepted:
27
08
2020
entrez:
30
10
2020
pubmed:
31
10
2020
medline:
31
10
2020
Statut:
epublish
Résumé
The treatment of allergic diseases, such as asthma, with both conventional and novel therapies presents a challenge both in terms of optimal effect and cost. On the other hand, traditional therapies utilizing natural products such as onion have been in use for centuries with demonstrated efficacy and safety but without much knowledge of their mechanims of action. In this study, we investigated if the anti-inflammatory effects of onion bulb extract (OBE) are mediated
Identifiants
pubmed: 33123005
doi: 10.3389/fphar.2020.551683
pmc: PMC7567342
doi:
Types de publication
Journal Article
Langues
eng
Pagination
551683Informations de copyright
Copyright © 2020 El-Hashim, Khajah, Orabi, Balakrishnan, Sary and Abdelali.
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