Ovarian malignant mixed Müllerian tumor: a rare case report from Tanzania.


Journal

Journal of surgical case reports
ISSN: 2042-8812
Titre abrégé: J Surg Case Rep
Pays: England
ID NLM: 101560169

Informations de publication

Date de publication:
Oct 2020
Historique:
received: 17 08 2020
accepted: 03 09 2020
entrez: 30 10 2020
pubmed: 31 10 2020
medline: 31 10 2020
Statut: epublish

Résumé

Malignant mixed Müllerian tumor of the ovary is rare aggressive tumor that is histologically defined by the presence of malignant epithelial and stromal components. We report a 37-year-old woman who consulted our facility complaining of abdominal distention and a painful palpable mass over her lower abdomen. Physical examination including computerized tomography revealed a complex cystic mass lesion on the left ovary with extensive omental involvement. Ovarian cancer was suspected and the patient underwent debulking surgery. The histopathology of the specimen revealed a high-grade tumor composed of both malignant epithelial and sarcomatous elements. Both epithelial and stromal components stained positive for p53 immunostaining. Before the initiation of chemotherapy, on 5th day postoperation, the patient was found unresponsive. The stage of the disease seems to be the most important prognostic factor, thus emphasis should be made to identify it in earlier stages.

Identifiants

pubmed: 33123343
doi: 10.1093/jscr/rjaa406
pii: rjaa406
pmc: PMC7571862
doi:

Types de publication

Case Reports

Langues

eng

Pagination

rjaa406

Informations de copyright

Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020.

Références

Br J Cancer. 2003 Mar 10;88(5):654-7
pubmed: 12618869
Gynecol Oncol. 2007 Jun;105(3):657-61
pubmed: 17395252
Cancer. 1995 Oct 1;76(7):1209-13
pubmed: 8630899
Gynecol Oncol. 2003 Nov;91(2):426-8
pubmed: 14599878
Ann Oncol. 1995 Oct;6(8):755-8
pubmed: 8589011
Int J Gynecol Cancer. 2008 Jan-Feb;18(1):22-9
pubmed: 17451459
Cancer. 2004 May 15;100(10):2148-53
pubmed: 15139057
Gynecol Oncol. 2004 May;93(2):506-12
pubmed: 15099970
Int J Gynecol Cancer. 2007 Mar-Apr;17(2):316-24
pubmed: 17362309
Gynecol Oncol. 2006 Jan;100(1):128-32
pubmed: 16213011

Auteurs

Angela Pallangyo (A)

Department of Pathology, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

Jeremia J Pyuza (JJ)

Department of Pathology, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

Alice A Andongolile (AA)

Kilimanjaro Clinical Research Institute, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

Daniel Mbwambo (D)

Department of Pathology, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

Jackson P Claver (JP)

Department of Pathology, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

Ummil-Khairat Koosa (UK)

Department of Pathology, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

Kennedy Lema (K)

Department of Pathology, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

Patrick Amsi (P)

Department of Pathology, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

Gilbert Nkya (G)

Department of Pathology, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

Alex Mremi (A)

Department of Pathology, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

Classifications MeSH