A loosening prosthesis in a dialysis patient.
dialysis
hypophosphataemia
osteomalacia
periprosthetic fracture
Journal
Clinical kidney journal
ISSN: 2048-8505
Titre abrégé: Clin Kidney J
Pays: England
ID NLM: 101579321
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
28
03
2019
accepted:
15
05
2019
entrez:
30
10
2020
pubmed:
26
6
2019
medline:
26
6
2019
Statut:
epublish
Résumé
A haemodialysis patient with periprosthetic fractures and a history of corticosteroid use was referred for assessment for bone mineral disorders. Mixed renal osteodystrophy was diagnosed following a bone biopsy. Correction for vitamin D insufficiency did not improve the clinical signs, which prompted a potential diagnosis of hypophosphataemic osteomalacia to be considered. No causes for hypophosphataemia were found, except for phosphate dietary restrictions. Phosphorus supplementation was administered, resulting in an upturn in bone biochemical and histological parameters and increased bone mineral density, thus confirming the diagnosis of hypophosphataemic osteomalacia due to low phosphate intake. Characteristic features related to this diagnosis are shown from three repeated bone biopsies performed during the course of patient follow-up.
Identifiants
pubmed: 33123365
doi: 10.1093/ckj/sfz078
pii: sfz078
pmc: PMC7577770
doi:
Types de publication
Case Reports
Langues
eng
Pagination
897-899Informations de copyright
© The Author(s) 2019. Published by Oxford University Press on behalf of ERA-EDTA.
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