[Prevalence of multiresistant gram-negative bacteria in inhabitants of long-term care facilities in 2019 in Thuringia].
Prävalenz von multiresistenten gramnegativen Erregern bei Bewohnern von stationären Pflegeeinrichtungen 2019 in Thüringen.
Antibiotics
Hygiene
MDRGN
Nursing homes
Risk factors
Journal
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
ISSN: 1437-1588
Titre abrégé: Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
Pays: Germany
ID NLM: 101181368
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
22
06
2020
accepted:
07
10
2020
pubmed:
31
10
2020
medline:
27
11
2020
entrez:
30
10
2020
Statut:
ppublish
Résumé
Multidrug-resistant gram-negative bacteria (MDRGN) pose an emerging threat in German hospitals and in the outpatient sector. However, only few studies have investigated the prevalence of MDRGN in nonhospital settings and the associated risk factors for colonization. In our study we determined the prevalence of MDRGN in inhabitants of long-term care facilities (LTCFs) and associated risk factors for colonization in the region Weimar, Weimarer Land, and Jena. Between May and August 2019, deep rectal swabs were taken from 307 inhabitants of 13 facilities and examined microbiologically for the presence of MDRGN. Furthermore, using a standardized questionnaire, the characteristics of the inhabitants were collected and their association with the likelihood for colonization with MDRGN was analyzed. MDRGN were found in 59 swabs, predominantly Escherichia coli (95%). The weighted prevalence of extended spectrum beta-lactamase-producing bacteria was 19.1% and for MDRGN with additional resistances to fluoroquinolones was 12.3%. Resistances to carbapenems or carbapenemases were not found. Multivariable as well as univariable analysis recognized the presence of chronic wounds to be a potential risk factor (OR: 2,66 [95 %-CI: 1,54-4,60]). Additionally, the univariable analysis detected the necessity of a wheelchair and the accommodation in double rooms as risk factors. The prevalence of MDRGN found in our study is similar to findings of previous German studies. The result shows the importance of strict compliance with basic hygiene guidelines for all inhabitants of LTCFs for the prevention of transmission of MDRGN.
Sections du résumé
BACKGROUND
BACKGROUND
Multidrug-resistant gram-negative bacteria (MDRGN) pose an emerging threat in German hospitals and in the outpatient sector. However, only few studies have investigated the prevalence of MDRGN in nonhospital settings and the associated risk factors for colonization.
OBJECTIVE
OBJECTIVE
In our study we determined the prevalence of MDRGN in inhabitants of long-term care facilities (LTCFs) and associated risk factors for colonization in the region Weimar, Weimarer Land, and Jena.
METHODS
METHODS
Between May and August 2019, deep rectal swabs were taken from 307 inhabitants of 13 facilities and examined microbiologically for the presence of MDRGN. Furthermore, using a standardized questionnaire, the characteristics of the inhabitants were collected and their association with the likelihood for colonization with MDRGN was analyzed.
RESULTS
RESULTS
MDRGN were found in 59 swabs, predominantly Escherichia coli (95%). The weighted prevalence of extended spectrum beta-lactamase-producing bacteria was 19.1% and for MDRGN with additional resistances to fluoroquinolones was 12.3%. Resistances to carbapenems or carbapenemases were not found. Multivariable as well as univariable analysis recognized the presence of chronic wounds to be a potential risk factor (OR: 2,66 [95 %-CI: 1,54-4,60]). Additionally, the univariable analysis detected the necessity of a wheelchair and the accommodation in double rooms as risk factors.
DISCUSSION
CONCLUSIONS
The prevalence of MDRGN found in our study is similar to findings of previous German studies. The result shows the importance of strict compliance with basic hygiene guidelines for all inhabitants of LTCFs for the prevention of transmission of MDRGN.
Identifiants
pubmed: 33125505
doi: 10.1007/s00103-020-03236-2
pii: 10.1007/s00103-020-03236-2
doi:
Types de publication
Journal Article
Langues
ger
Sous-ensembles de citation
IM