The transcriptomic signature of the aging podocyte.
Journal
Kidney international
ISSN: 1523-1755
Titre abrégé: Kidney Int
Pays: United States
ID NLM: 0323470
Informations de publication
Date de publication:
11 2020
11 2020
Historique:
received:
02
07
2020
revised:
31
07
2020
accepted:
03
08
2020
entrez:
31
10
2020
pubmed:
1
11
2020
medline:
18
11
2020
Statut:
ppublish
Résumé
Aging is the strongest independent risk factor for chronic kidney disease. Glomerular epithelial cells are unable to proliferate and have limited ability to renew; therefore, podocytes must maintain a delicate intracellular homeostasis that enables them to function and adapt to stress endured during the human life span. Here, Wang et al. performed unbiased transcriptomic analysis of aging podocytes and identified important novel regulators.
Identifiants
pubmed: 33126968
pii: S0085-2538(20)30955-8
doi: 10.1016/j.kint.2020.08.004
pmc: PMC9380427
mid: NIHMS1827431
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Comment
Langues
eng
Sous-ensembles de citation
IM
Pagination
1079-1081Subventions
Organisme : NIDDK NIH HHS
ID : R01 DK076077
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK087635
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK105821
Pays : United States
Commentaires et corrections
Type : CommentOn
Informations de copyright
Copyright © 2020 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.
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