Intraprostatic Tumor Segmentation on PSMA PET Images in Patients with Primary Prostate Cancer with a Convolutional Neural Network.


Journal

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
ISSN: 1535-5667
Titre abrégé: J Nucl Med
Pays: United States
ID NLM: 0217410

Informations de publication

Date de publication:
01 06 2021
Historique:
received: 31 07 2020
accepted: 07 10 2020
pubmed: 1 11 2020
medline: 27 8 2021
entrez: 31 10 2020
Statut: ppublish

Résumé

Accurate delineation of the intraprostatic gross tumor volume (GTV) is a prerequisite for treatment approaches in patients with primary prostate cancer (PCa). Prostate-specific membrane antigen PET (PSMA PET) may outperform MRI in GTV detection. However, visual GTV delineation underlies interobserver heterogeneity and is time consuming. The aim of this study was to develop a convolutional neural network (CNN) for automated segmentation of intraprostatic tumor (GTV-CNN) in PSMA PET.

Identifiants

pubmed: 33127624
pii: jnumed.120.254623
doi: 10.2967/jnumed.120.254623
pmc: PMC8729869
doi:

Substances chimiques

Gallium Isotopes 0
Gallium Radioisotopes 0
gallium 68 PSMA-11 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

823-828

Informations de copyright

COPYRIGHT © 2021 by the Society of Nuclear Medicine and Molecular Imaging.

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Auteurs

Dejan Kostyszyn (D)

Division of Medical Physics, Department of Radiation Oncology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Faculty of Engineering, University of Freiburg, Freiburg, Germany.

Tobias Fechter (T)

Division of Medical Physics, Department of Radiation Oncology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
German Cancer Consortium (DKTK), Partner Site Freiburg, Germany.
Department of Radiation Oncology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Nico Bartl (N)

German Cancer Consortium (DKTK), Partner Site Freiburg, Germany.
Department of Radiation Oncology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Anca L Grosu (AL)

German Cancer Consortium (DKTK), Partner Site Freiburg, Germany.
Department of Radiation Oncology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Christian Gratzke (C)

Department of Urology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

August Sigle (A)

Department of Urology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Michael Mix (M)

Department of Nuclear Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Juri Ruf (J)

Department of Nuclear Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Thomas F Fassbender (TF)

Department of Nuclear Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Selina Kiefer (S)

Institute for Surgical Pathology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Alisa S Bettermann (AS)

Department of Radiation Oncology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Nils H Nicolay (NH)

German Cancer Consortium (DKTK), Partner Site Freiburg, Germany.
Department of Radiation Oncology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Simon Spohn (S)

German Cancer Consortium (DKTK), Partner Site Freiburg, Germany.
Department of Radiation Oncology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Maria U Kramer (MU)

Department of Radiation Oncology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Peter Bronsert (P)

German Cancer Consortium (DKTK), Partner Site Freiburg, Germany.
Institute for Surgical Pathology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Hongqian Guo (H)

Department of Urology, Medical School of Nanjing University, Affiliated Drum Tower Hospital, Nanjing, China.

Xuefeng Qiu (X)

Department of Urology, Medical School of Nanjing University, Affiliated Drum Tower Hospital, Nanjing, China.

Feng Wang (F)

Department of Nuclear Medicine, Medical School of Nanjing University, Affiliated Drum Tower Hospital, Nanjing, China.

Christoph Henkenberens (C)

Department of Radiation Oncology, Hannover Medical School, Hannover, Germany.

Rudolf A Werner (RA)

Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany.

Dimos Baltas (D)

Division of Medical Physics, Department of Radiation Oncology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
German Cancer Consortium (DKTK), Partner Site Freiburg, Germany.

Philipp T Meyer (PT)

Department of Nuclear Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Thorsten Derlin (T)

Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany.

Mengxia Chen (M)

Department of Urology, Medical School of Nanjing University, Affiliated Drum Tower Hospital, Nanjing, China.

Constantinos Zamboglou (C)

German Cancer Consortium (DKTK), Partner Site Freiburg, Germany constantinos.zamboglou@uniklinik-freiburg.de.
Department of Radiation Oncology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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Classifications MeSH