Hypogonadism and bone health in men with HIV.

Antiretroviral Therapy, Highly Active / adverse effects Bone and Bones / metabolism HIV Infections / drug therapy Humans Hypogonadism / diagnosis Male Osteoporosis / diagnosis Prevalence Quality of Life

Journal

The lancet. HIV
ISSN: 2352-3018
Titre abrégé: Lancet HIV
Pays: Netherlands
ID NLM: 101645355

Informations de publication

Date de publication:
11 2020
Historique:
received: 10 04 2020
revised: 30 06 2020
accepted: 03 07 2020
pubmed: 1 11 2020
medline: 19 12 2020
entrez: 31 10 2020
Statut: ppublish

Résumé

The advent of new classes of antiretroviral drugs has improved the survival of people with HIV, and several ageing-related conditions, including hypogonadism and osteoporosis, have emerged. However, both are silent conditions, and are underestimated, underdiagnosed, and not adequately treated. Several factors, including the effects of the virus, antiretroviral therapy, lifestyle factors, and comorbidities, contribute to testicular dysfunction, which in turn has important effects on bone health. The prevalence of hypogonadism is approximately 20% among men with HIV, but extreme variability in the laboratory and clinical assessment of hypogonadism is reported. The prevalence of osteoporosis is 10-30%, but the poor quality of most studies does not allow definitive conclusions on clinical management. Nonetheless, the early and detailed evaluation of gonadal function and bone health is crucial for improving the quality of life of men with HIV.

Identifiants

DOI: 10.1016/S2352-3018(20)30236-8 PMID: 33128905
pubmed: 33128905
pii: S2352-3018(20)30236-8
doi: 10.1016/S2352-3018(20)30236-8
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e782-e790

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Auteurs

Filippo Maffezzoni (F)

Department of Medicine, Unit of Endocrinology and Metabolism, L'Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia, Italy.

Teresa Porcelli (T)

Endocrinology, Montichiari Hospital, L'Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia, Italy.

Andrea Delbarba (A)

Department of Medicine, Unit of Endocrinology and Metabolism, L'Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia, Italy.

Letizia Chiara Pezzaioli (LC)

Department of Clinical and Experimental Sciences, Unit of Endocrinology and Metabolism, University of Brescia and L'Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia, Italy.

Martina Properzi (M)

Department of Clinical and Experimental Sciences, Unit of Infectious and Tropical Diseases, University of Brescia and L'Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia, Italy.

Carlo Cappelli (C)

Department of Clinical and Experimental Sciences, Unit of Endocrinology and Metabolism, University of Brescia and L'Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia, Italy.

Francesco Castelli (F)

Department of Clinical and Experimental Sciences, Unit of Infectious and Tropical Diseases, University of Brescia and L'Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia, Italy.

Maria Eugenia Quiros-Roldan (ME)

Department of Clinical and Experimental Sciences, Unit of Infectious and Tropical Diseases, University of Brescia and L'Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia, Italy.

Alberto Ferlin (A)

Department of Clinical and Experimental Sciences, Unit of Endocrinology and Metabolism, University of Brescia and L'Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia, Italy. Electronic address: alberto.ferlin@unibs.it.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Association de médicaments › Thérapie antirétrovirale hautement active › Hypogonadism and bone health in men with HIV.
questionsmedicales.fr › Tissus › Tissu conjonctif › Os et tissu osseux › Hypogonadism and bone health in men with HIV.
questionsmedicales.fr › Maladies du système immunitaire › Déficits immunitaires › Infections à VIH › Hypogonadism and bone health in men with HIV.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Hypogonadism and bone health in men with HIV.
questionsmedicales.fr › Maladies endocriniennes › Troubles gonadiques › Hypogonadisme › Hypogonadism and bone health in men with HIV.
questionsmedicales.fr › Maladies métaboliques et nutritionnelles › Maladies métaboliques › Maladies osseuses métaboliques › Ostéoporose › Hypogonadism and bone health in men with HIV.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Registre civil › Morbidité › Prévalence › Hypogonadism and bone health in men with HIV.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Mesures épidémiologiques › Démographie › État de santé › Qualité de vie › Hypogonadism and bone health in men with HIV.