Asymptomatic hypoxia in COVID-19 is associated with poor outcome.
02 sat
COVID-19
D-dimers
Happy
Hypocapnia
Hypoxemia
Hypoxia
Low dose CT-scan
Journal
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
ISSN: 1878-3511
Titre abrégé: Int J Infect Dis
Pays: Canada
ID NLM: 9610933
Informations de publication
Date de publication:
Jan 2021
Jan 2021
Historique:
received:
24
09
2020
revised:
22
10
2020
accepted:
23
10
2020
pubmed:
2
11
2020
medline:
15
1
2021
entrez:
1
11
2020
Statut:
ppublish
Résumé
Describe and evaluate the outcome of a coronavirus disease-2019 (COVID-19) patient without shortness of breath. We retrospectively collected data from COVID-19 patients diagnosed and cared for in Marseille, France. We selected data from patients who at admission, had a low dose CT scanner, dyspnea status, and oxygen saturation available. Blood gas was analyzed in a sample subset of patients. Among 1712 patients with COVID-19, we report that 1107 (64.7%) do not complain of shortness of breath at admission. The low-dose computed tomography (LDCT) scan showed signs compatible with pneumonia in 757/1,107 (68.4%) of patients without dyspnea. In a subset of patients who had underwent at least one blood gas analysis (n = 161) and presented without dyspnea at admission, 28.1% (27/96) presented with a hypoxemia/hypocapnia syndrome. Asymptomatic hypoxia was associated with a very poor outcome (33.3% were transferred to the ICU and 25.9% died). The absence of shortness of breath in an old patient with comorbidity merit medical attention and should not be considered as a good sign of well-being. The poor prognosis of asymptomatic hypoxia, highlight the severity of this mild clinical presentation. In these patients, pulse oximetry is an important mean to predict the outcome along with news score and LDCT scanner.
Identifiants
pubmed: 33130200
pii: S1201-9712(20)32271-2
doi: 10.1016/j.ijid.2020.10.067
pmc: PMC7604151
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
233-238Informations de copyright
Copyright © 2020 The Authors. Published by Elsevier Ltd.. All rights reserved.
Références
N Engl J Med. 2020 Apr 30;382(18):1708-1720
pubmed: 32109013
Thromb Res. 2020 Jul;191:148-150
pubmed: 32381264
Lancet Infect Dis. 2020 Oct;20(10):1135-1140
pubmed: 32526193
Science. 2020 May 1;368(6490):455-456
pubmed: 32355007
N Engl J Med. 1988 Nov 24;319(21):1369-73
pubmed: 3185647
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
JAMA Netw Open. 2020 Apr 1;3(4):e205619
pubmed: 32275319
Eur J Clin Microbiol Infect Dis. 2020 Jun;39(6):1059-1061
pubmed: 32342252
Lancet. 2020 Mar 28;395(10229):1054-1062
pubmed: 32171076
Travel Med Infect Dis. 2020 Sep - Oct;37:101875
pubmed: 32898703
Tidsskr Nor Laegeforen. 2020 Apr 11;140(7):
pubmed: 32378842
Travel Med Infect Dis. 2020 Jul - Aug;36:101791
pubmed: 32593867
Intensive Care Med. 2020 Feb;46(2):357-360
pubmed: 32025779
Am J Respir Crit Care Med. 2020 Aug 1;202(3):356-360
pubmed: 32539537